Short Description

NGS genetic DNA test detecets for variant and mutation detection in MFN2 gene for CMT2A2

PreTest Information

Clinical History of Patient who is going for MFN2 Gene CMT2A2 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with MFN2 Gene CMT2A2

Detail Description

MFN2 Gene CMT2A2 NGS Genetic DNA Test: Symptoms, Diagnosis and Cost

Charcot-Marie-Tooth disease (CMT) is a group of inherited neurological disorders that affect the peripheral nerves. One of the subtypes of CMT is CMT2A2, which is caused by mutations in the MFN2 gene. NGS genetic DNA testing can help diagnose CMT2A2 and other genetic disorders. In this blog, we will discuss the symptoms, diagnosis and cost of the MFN2 Gene CMT2A2 NGS Genetic DNA Test.

Symptoms of CMT2A2

The symptoms of CMT2A2 usually start in adolescence or early adulthood. The most common symptoms include:

• Weakness in the feet and legs
• Tingling or numbness in the feet and legs
• Difficulty walking
• Loss of muscle mass in the lower legs and feet
• High arches in the feet (pes cavus)
• Hammertoes or claw toes

CMT2A2 can also cause symptoms in the hands and arms, including weakness and loss of muscle mass. Some people with CMT2A2 may have difficulty with fine motor skills, such as writing or buttoning clothes.

Diagnosis of CMT2A2

Diagnosing CMT2A2 can be challenging because the symptoms can be similar to other neurological disorders. However, genetic testing can help confirm a diagnosis of CMT2A2. The MFN2 gene is responsible for producing a protein called mitofusin 2, which is involved in the maintenance of mitochondria in cells. Mutations in the MFN2 gene can disrupt the function of mitochondria, leading to the symptoms of CMT2A2.

NGS genetic DNA testing can analyze the MFN2 gene and other genes associated with CMT and other neurological disorders. This type of testing can identify specific genetic mutations that may be causing the symptoms.

Cost of MFN2 Gene CMT2A2 NGS Genetic DNA Test

The cost of the MFN2 Gene CMT2A2 NGS Genetic DNA Test in India is approximately INR 20,000. This cost may vary depending on the specific testing laboratory and any additional tests that may be required.

Conclusion

CMT2A2 is a rare subtype of Charcot-Marie-Tooth disease that is caused by mutations in the MFN2 gene. NGS genetic DNA testing can help diagnose CMT2A2 and other genetic disorders. If you or a loved one are experiencing symptoms of CMT2A2, talk to your doctor about genetic testing options. The cost of the MFN2 Gene CMT2A2 NGS Genetic DNA Test may be a factor to consider, but early diagnosis and treatment can improve outcomes for people with CMT2A2.

At DNA Labs India, we offer a comprehensive range of genetic testing services, including NGS genetic DNA testing. Contact us today to learn more about our services and how we can help diagnose genetic disorders.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for MFN2 Gene CMT2A2 NGS Genetic DNA Test