Short Description

This assay is an early and sensitive indicator of Vitamin B12 (Cobalamin) deficiency. MMA is a sensitive indicator which detects early Vitamin B12 deficiency. In pediatric patients, elevated MMA values indicate a probable Methylmalonic acidemia whereas in adults, it is indicative of Cobalamin deficiency.

PreTest Information

Submit first morning urine sample. Provide a brief clinical and drug history.

Detail Description

Methylmalonic Acid Quantitative Urine Test: Cost, Symptoms, and Diagnosis

Are you experiencing fatigue, weakness, or numbness in your extremities? These could be symptoms of methylmalonic acidemia, a rare genetic disorder that affects the body's ability to process certain proteins and fats. Fortunately, a methylmalonic acid quantitative urine test can help diagnose this condition and others that affect the body's metabolism.

Symptoms of Methylmalonic Acidemia

Methylmalonic acidemia is a metabolic disorder that affects about 1 in 50,000 people worldwide. Symptoms typically appear in infancy or early childhood and can include:

• Failure to thrive
• Vomiting
• Dehydration
• Low muscle tone
• Lethargy
• Seizures

In some cases, symptoms may not appear until later in life, and can include:

• Chronic fatigue
• Numbness or tingling in the hands and feet
• Muscle weakness
• Difficulty walking
• Vision and hearing problems

What is a Methylmalonic Acid Quantitative Urine Test?

A methylmalonic acid quantitative urine test is a diagnostic test that measures the levels of methylmalonic acid in a patient's urine. Methylmalonic acid is a byproduct of protein and fat metabolism that is normally excreted by the kidneys. Elevated levels of methylmalonic acid in the urine can indicate a problem with the body's ability to process certain proteins and fats, which can lead to a buildup of toxic substances in the body.

The test is typically performed on a urine sample collected over a 24-hour period. The patient will be instructed to collect all urine produced during this time period in a special container provided by the lab. The sample will then be sent to a laboratory for analysis.

Diagnosis and Treatment

If the results of a methylmalonic acid quantitative urine test indicate elevated levels of methylmalonic acid, further testing may be necessary to confirm a diagnosis of methylmalonic acidemia or another metabolic disorder. Treatment for methylmalonic acidemia typically involves a low-protein diet, special vitamin supplements, and medications to help the body eliminate excess methylmalonic acid.

Cost of Methylmalonic Acid Quantitative Urine Test in India

The cost of a methylmalonic acid quantitative urine test in India can vary depending on the location and the lab performing the test. At DNA Labs India, the cost of this test is INR 3,500.

Conclusion

If you are experiencing symptoms of methylmalonic acidemia or another metabolic disorder, a methylmalonic acid quantitative urine test can help diagnose the problem. Contact DNA Labs India to schedule your test and get the answers you need to start feeling better.