Short Description

NGS genetic DNA test detecets for variant and mutation detection in LPA gene for Coronary artery disease, susceptibility to

PreTest Information

Clinical History of Patient who is going for LPA Gene Coronary artery disease, susceptibility to NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Coronary artery disease, susceptibility to

Detail Description

LPA Gene and Coronary Artery Disease: Understanding the Susceptibility with NGS Genetic DNA Test

Coronary artery disease (CAD) is a leading cause of death worldwide. It is a condition where plaque builds up in the arteries that supply blood to the heart, leading to a reduction in blood flow. The risk of developing CAD is influenced by a combination of environmental and genetic factors. One of the genes that have been linked to an increased risk of developing CAD is the LPA gene.

What is the LPA Gene?

The LPA gene provides instructions for making a protein called lipoprotein(a) or Lp(a). Lp(a) is a type of low-density lipoprotein (LDL) cholesterol that is associated with an increased risk of developing CAD. Lp(a) can accumulate in the walls of arteries and contribute to the formation of plaque.

How does the LPA Gene Affect the Risk of Developing CAD?

Studies have shown that people who have a variant of the LPA gene that produces high levels of Lp(a) are at an increased risk of developing CAD. In fact, having high levels of Lp(a) can increase the risk of CAD by up to 70%.

Diagnosis of LPA Gene and CAD

The diagnosis of LPA gene and CAD is typically made through a combination of clinical evaluation, imaging tests, and genetic testing. Symptoms of CAD may include chest pain, shortness of breath, and fatigue. Imaging tests such as a coronary angiogram or a cardiac CT scan can help determine the extent of plaque buildup in the arteries. Genetic testing can be used to identify variants in the LPA gene that may increase the risk of CAD.

NGS Genetic DNA Test for LPA Gene and CAD

Next-generation sequencing (NGS) is a powerful tool that can be used to identify genetic variants that may increase the risk of CAD. NGS technology allows for the sequencing of large amounts of genetic data quickly and accurately. This technology can be used to identify variants in the LPA gene that may be associated with an increased risk of CAD.

Cost of NGS Genetic DNA Test for LPA Gene and CAD

The cost of an NGS genetic DNA test for the LPA gene and CAD can vary depending on the provider and the specific tests that are performed. On average, the cost of an NGS genetic DNA test for LPA Gene and CAD in India is around INR 20,000.

Conclusion

The LPA gene has been linked to an increased risk of developing CAD. Genetic testing using NGS technology can be used to identify variants in the LPA gene that may increase the risk of CAD. Early identification of genetic variants associated with CAD can help individuals take steps to reduce their risk of developing this condition. If you have a family history of CAD or are experiencing symptoms of this condition, talk to your healthcare provider about the possibility of genetic testing.