Short Description

NGS genetic DNA test detecets for variant and mutation detection in LMNA gene for Lipodystrophy type 2, familial partial

PreTest Information

Clinical History of Patient who is going for LMNA Gene Lipodystrophy type 2, familial partial NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Lipodystrophy type 2, familial partial

Detail Description

LMNA Gene Lipodystrophy Type 2: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost in India

Lipodystrophy is a rare genetic disorder that affects fat metabolism in the body. It results in abnormal distribution of body fat leading to various complications. There are different types of lipodystrophies, and one of them is familial partial lipodystrophy type 2 caused by mutations in the LMNA gene. This blog post will focus on the symptoms, diagnosis, and cost of NGS genetic DNA test for LMNA gene lipodystrophy type 2 in India.

Symptoms of LMNA Gene Lipodystrophy Type 2

The symptoms of LMNA gene lipodystrophy type 2 usually appear during late childhood or early adolescence. The affected individuals have a characteristic body shape with loss of subcutaneous fat from the limbs, buttocks, and trunk. The fat is redistributed to other parts of the body such as the neck, face, and abdomen. This can give the appearance of a "buffalo hump" on the upper back and a protruding abdomen. Other symptoms of LMNA gene lipodystrophy type 2 may include:

• Insulin resistance
• Diabetes mellitus
• High triglycerides and cholesterol levels
• Hypertension
• Enlarged liver and spleen
• Polycystic ovary syndrome in females

Diagnosis of LMNA Gene Lipodystrophy Type 2

LMNA gene lipodystrophy type 2 is diagnosed based on clinical features, family history, and genetic testing. A physical examination may reveal the characteristic body shape and other symptoms such as enlarged liver and spleen. Blood tests may show high triglycerides and cholesterol levels, insulin resistance, and diabetes mellitus. Genetic testing can confirm the diagnosis by identifying mutations in the LMNA gene.

NGS Genetic DNA Test Cost for LMNA Gene Lipodystrophy Type 2 in India

Next-generation sequencing (NGS) is a powerful genetic testing technique that can analyze multiple genes simultaneously. It is a useful tool for diagnosing rare genetic disorders such as LMNA gene lipodystrophy type 2. The cost of NGS genetic DNA test for LMNA gene lipodystrophy type 2 in India may vary depending on the laboratory and the type of test. On average, the cost of NGS genetic DNA test for LMNA gene lipodystrophy type 2 in India is around INR 20,000.

Conclusion

LMNA gene lipodystrophy type 2 is a rare genetic disorder that affects fat metabolism in the body. It can cause various complications such as insulin resistance, diabetes mellitus, and high triglycerides and cholesterol levels. LMNA gene lipodystrophy type 2 is diagnosed based on clinical features, family history, and genetic testing. NGS genetic DNA test is a useful tool for diagnosing LMNA gene lipodystrophy type 2 in India with an average cost of around INR 20,000. Early diagnosis and management of LMNA gene lipodystrophy type 2 can help prevent complications and improve the quality of life of affected individuals.

For more information on genetic testing for LMNA gene lipodystrophy type 2 in India, contact DNA Labs India, a leading provider of genetic testing services in India.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for LMNA Gene Lipodystrophy type 2, familial partial NGS Genetic DNA Test