What is LEMD3 Gene Buschke-Ollendorff Syndrome?

LEMD3 Gene Buschke-Ollendorff Syndrome is a rare genetic disorder that affects the skin and bones. It is caused by mutations in the LEMD3 gene. The syndrome is characterized by the development of multiple connective tissue nevi, which are benign tumors of the skin and subcutaneous tissue. These nevi are often present at birth or appear during childhood. The syndrome is also associated with bone abnormalities, including osteopoikilosis, which is the presence of multiple benign bone lesions.

NGS Genetic DNA Test for LEMD3 Gene Buschke-Ollendorff Syndrome

DNA Labs India offers Next-Generation Sequencing (NGS) Genetic DNA Test for LEMD3 Gene Buschke-Ollendorff Syndrome. This test can detect mutations in the LEMD3 gene that cause the syndrome. The test is performed using a small blood sample and is highly accurate. The cost of the test is INR 20000.

Symptoms of LEMD3 Gene Buschke-Ollendorff Syndrome

• Multiple connective tissue nevi
• Osteopoikilosis
• Abnormalities of the nails
• Abnormalities of the teeth
• Benign tumors of the breast

Diagnosis of LEMD3 Gene Buschke-Ollendorff Syndrome

LEMD3 Gene Buschke-Ollendorff Syndrome can be diagnosed through a combination of clinical examination and genetic testing. A dermatologist or geneticist can perform a physical exam to look for the characteristic skin and bone abnormalities associated with the syndrome. Genetic testing, such as the NGS Genetic DNA Test offered by DNA Labs India, can confirm the diagnosis by detecting mutations in the LEMD3 gene.

Conclusion

LEMD3 Gene Buschke-Ollendorff Syndrome is a rare genetic disorder that can cause skin and bone abnormalities. The syndrome can be diagnosed through clinical examination and genetic testing, such as the NGS Genetic DNA Test offered by DNA Labs India. The cost of the test is INR 20000. If you suspect that you or a loved one may have LEMD3 Gene Buschke-Ollendorff Syndrome, it is important to seek medical advice from a dermatologist or geneticist.