Short Description

NGS genetic DNA test detecets for variant and mutation detection in LCT gene for Lactase deficiency, congenital

PreTest Information

Clinical History of Patient who is going for LCT Gene Lactase deficiency, congenital NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Lactase deficiency, congenital

Detail Description

LCT Gene and Lactase Deficiency: Understanding the Symptoms, Diagnosis, and Cost of NGS Genetic DNA Test in India

Lactase deficiency is a common condition that affects a significant percentage of the world’s population. It is caused by the body’s inability to produce enough lactase, an enzyme that helps digest lactose, the sugar found in milk and dairy products. This condition can be either congenital or acquired and can lead to a range of symptoms, including bloating, gas, diarrhea, and abdominal pain. In this blog, we will explore the LCT gene, lactase deficiency, its symptoms, diagnosis, and the cost of NGS genetic DNA test in India.

Understanding the LCT Gene

The LCT gene is responsible for producing lactase enzyme, which is essential in the digestion of lactose. The gene is located on chromosome 2 and is made up of 49 exons. Mutations in the LCT gene can lead to lactase deficiency, which can be either congenital or acquired.

Lactase Deficiency

Lactase deficiency can be either congenital or acquired. Congenital lactase deficiency is a rare condition that is inherited from parents who carry the mutated LCT gene. Infants with this condition are unable to digest lactose and usually develop severe diarrhea and dehydration. Acquired lactase deficiency, on the other hand, is more common and occurs as a result of the body’s natural decrease in lactase production as we age. This condition can also be triggered by certain medical conditions, such as celiac disease, Crohn’s disease, and chemotherapy.

Symptoms of Lactase Deficiency

The symptoms of lactase deficiency can range from mild to severe and can include:

• Bloating
• Gas
• Diarrhea
• Abdominal pain
• Nausea

These symptoms usually occur within 30 minutes to 2 hours after consuming milk or dairy products and can last for several hours.

Diagnosis of Lactase Deficiency

The diagnosis of lactase deficiency is usually made based on the patient’s symptoms and medical history. In some cases, a lactose tolerance test may be performed to confirm the diagnosis. This test involves consuming a lactose solution and measuring the level of glucose in the blood at regular intervals.

NGS Genetic DNA Test for Lactase Deficiency

Next-generation sequencing (NGS) genetic DNA test is a highly advanced technique that allows for the detection of genetic mutations in the LCT gene. This test can help diagnose lactase deficiency and can also identify carriers of the condition. The cost of NGS genetic DNA test in India can vary depending on the laboratory and the specific test being performed. On average, the cost of NGS genetic DNA test for lactase deficiency in India is around INR 20,000.

Conclusion

Lactase deficiency is a common condition that can cause a range of symptoms, including bloating, gas, diarrhea, and abdominal pain. Understanding the LCT gene, its mutations, and the symptoms of lactase deficiency can help in the diagnosis and treatment of this condition. NGS genetic DNA test is a highly advanced technique that can help diagnose lactase deficiency and identify carriers of the condition. If you suspect that you or a loved one may have lactase deficiency, it is important to speak to a healthcare professional for proper diagnosis and treatment.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for LCT Gene Lactase deficiency, congenital NGS Genetic DNA Test