Short Description

NGS genetic DNA test detecets for variant and mutation detection in LAMC3 gene for Cortical malformations, occipital

PreTest Information

Clinical History of Patient who is going for LAMC3 Gene Cortical malformations, occipital NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with LAMC3 Gene Cortical malformations, occipital NGS Genetic DNA Test gene LAMC3

Detail Description

LAMC3 Gene Cortical Malformations: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost

Cortical malformations are a group of brain disorders characterized by abnormal brain development. These malformations can occur in any part of the brain, but occipital cortical malformations are particularly common. One of the genes that have been implicated in cortical malformations is the LAMC3 gene.

The LAMC3 gene encodes a protein called laminin gamma-3, which is essential for the normal development of the brain. Mutations in this gene can lead to a range of cortical malformations, including pachygyria, polymicrogyria, and schizencephaly.

Symptoms of LAMC3 Gene Cortical Malformations

The symptoms of cortical malformations vary depending on the severity of the condition. In some cases, the malformations may be asymptomatic, while in others, they can cause severe neurological deficits.

Some common symptoms of LAMC3 gene cortical malformations include:

• Developmental delay
• Intellectual disability
• Seizures
• Muscle weakness
• Visual impairments
• Speech difficulties
• Behavioral problems

Diagnosis of LAMC3 Gene Cortical Malformations

The diagnosis of cortical malformations can be challenging, as the symptoms can vary widely and may be similar to other neurological conditions. However, there are several diagnostic tests that can help identify LAMC3 gene cortical malformations, including:

• Magnetic resonance imaging (MRI) of the brain
• Electroencephalogram (EEG)
• Genetic testing

Genetic testing is particularly important in the diagnosis of LAMC3 gene cortical malformations. Next-generation sequencing (NGS) genetic DNA testing can identify mutations in the LAMC3 gene and help confirm the diagnosis.

NGS Genetic DNA Test Cost for LAMC3 Gene Cortical Malformations

The cost of NGS genetic DNA testing for LAMC3 gene cortical malformations varies depending on the testing provider. At DNA Labs India, the cost of NGS genetic DNA testing for LAMC3 gene cortical malformations is INR 20,000.

This test involves the analysis of the LAMC3 gene to identify any mutations that may be causing cortical malformations. The test is non-invasive and can be performed using a simple blood or saliva sample.

Conclusion

LAMC3 gene cortical malformations can cause a range of neurological symptoms, including developmental delay, seizures, and intellectual disability. Diagnosis can be challenging, but NGS genetic DNA testing can help confirm the diagnosis and identify mutations in the LAMC3 gene. At DNA Labs India, this test is available for a cost of INR 20,000.

If you or a loved one is experiencing symptoms of cortical malformations, it is important to seek medical attention promptly. Early diagnosis and treatment can help improve outcomes and quality of life.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for LAMC3 Gene Cortical malformations, occipital NGS Genetic DNA Test