Short Description

NGS genetic DNA test detecets for variant and mutation detection in KLK4 gene for Amelogenesis imperfecta type 2A1

PreTest Information

Clinical History of Patient who is going for KLK4 Gene Amelogenesis imperfecta type 2A1 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with KLK4 Gene Amelogenesis imperfecta type 2A1 NGS Genetic DNA Test gene KLK4

Detail Description

Understanding Amelogenesis Imperfecta Type 2A1 and the KLK4 Gene

Amelogenesis Imperfecta Type 2A1 is a genetic disorder that affects the development of tooth enamel. It is caused by mutations in the KLK4 gene, which provides instructions for making a protein called kallikrein-related peptidase 4. This protein is essential for the normal development of tooth enamel.

Individuals with Amelogenesis Imperfecta Type 2A1 have thin, fragile, and discolored enamel that can easily chip and wear away. This can lead to tooth sensitivity, cavities, and an increased risk of tooth loss. Other common symptoms of Amelogenesis Imperfecta Type 2A1 include:

• Delayed eruption of teeth
• Abnormal tooth shape and size
• Enamel that appears pitted or grooved
• Yellow or brown discoloration of teeth
• Increased risk of dental caries and decay

Diagnosing Amelogenesis Imperfecta Type 2A1 typically involves a clinical examination of the teeth and a review of the patient's medical and dental history. However, a genetic DNA test can confirm the presence of mutations in the KLK4 gene and provide more information about the specific type of Amelogenesis Imperfecta present.

NGS Genetic DNA Test for KLK4 Gene Amelogenesis Imperfecta Type 2A1

NGS (Next Generation Sequencing) is a genetic testing method that allows for the rapid and accurate analysis of multiple genes, including the KLK4 gene. This type of DNA testing can identify genetic mutations associated with Amelogenesis Imperfecta Type 2A1 and provide valuable information for diagnosis and treatment.

The cost of an NGS genetic DNA test for KLK4 gene Amelogenesis Imperfecta Type 2A1 in India typically ranges from INR 20,000 to INR 25,000. This cost may vary depending on the testing facility and the specific type of test being performed.

Why Get Tested?

If you or a family member have symptoms of Amelogenesis Imperfecta Type 2A1, getting tested for mutations in the KLK4 gene can provide several benefits:

• Accurate diagnosis and classification of the specific type of Amelogenesis Imperfecta present
• Identification of other family members who may be at risk of developing the disorder
• Improved dental care and treatment options based on the specific genetic mutation present
• Access to genetic counseling and resources for managing the disorder

Conclusion

Amelogenesis Imperfecta Type 2A1 is a genetic disorder that affects tooth enamel development and can lead to a range of dental problems. Genetic testing for mutations in the KLK4 gene can provide valuable information for diagnosis, treatment, and genetic counseling. While the cost of NGS genetic DNA testing for KLK4 gene Amelogenesis Imperfecta Type 2A1 in India may vary, the benefits of testing can be significant for individuals and families affected by this disorder.

At DNA Labs India, we offer a range of genetic testing services, including NGS genetic DNA testing for Amelogenesis Imperfecta Type 2A1. Contact us today to learn more about our testing services and how we can help you.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for KLK4 Gene Amelogenesis imperfecta type 2A1 NGS Genetic DNA Test