Short Description

NGS genetic DNA test detecets for variant and mutation detection in KLF8 gene for Mental retardation non-syndromic

PreTest Information

Clinical History of Patient who is going for KLF8 Gene Mental retardation non-syndromic NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with KLF8 Gene Mental retardation non-syndromic

Detail Description

Unlocking the Mystery of Mental Retardation with DNA Testing

Mental retardation, also known as intellectual disability, is a condition that affects an individual's cognitive and adaptive functioning. It can be caused by genetic, environmental, or unknown factors. DNA testing has become an essential tool in diagnosing the genetic causes of mental retardation, and one of the genes that have been linked to the condition is the KLF8 gene.

The Role of KLF8 Gene in Mental Retardation

The KLF8 gene is a transcription factor that plays a critical role in brain development, particularly in the growth of neurons and the formation of synapses. Mutations in this gene have been associated with non-syndromic mental retardation, which means that the condition is not accompanied by any other physical or developmental abnormalities.

Non-syndromic mental retardation caused by KLF8 gene mutations is a rare condition, and its prevalence is not well-known. However, it has been reported in several studies that the severity of the condition varies among individuals with KLF8 mutations, and some may have mild to moderate intellectual disability, while others may have severe mental retardation.

Symptoms of KLF8 Gene Mental Retardation

The symptoms of non-syndromic mental retardation caused by KLF8 gene mutations can vary widely, but they usually involve intellectual disability and developmental delays. Children with this condition may have difficulty with language and communication, social skills, and activities of daily living. They may also exhibit behavioral problems, such as hyperactivity, aggression, and self-injurious behavior.

Diagnosis of KLF8 Gene Mental Retardation

The diagnosis of non-syndromic mental retardation caused by KLF8 gene mutations is typically made through genetic testing. Next-generation sequencing (NGS) technology is used to sequence the entire KLF8 gene and identify any mutations that may be present.

NGS technology is a high-throughput and cost-effective way to analyze genetic material and can detect mutations in multiple genes simultaneously. The cost of a KLF8 gene NGS genetic DNA test is around INR 20,000 in India.

If a mutation is detected in the KLF8 gene, the patient's family members may also be tested to determine if they carry the same mutation. This information can be useful for genetic counseling and family planning.

Conclusion

DNA testing has revolutionized the diagnosis and treatment of genetic disorders, including non-syndromic mental retardation caused by KLF8 gene mutations. Identifying the genetic cause of intellectual disability can help individuals and their families understand the condition and receive appropriate medical care and support. If you suspect that you or your child may have KLF8 gene mental retardation, consult a genetic counselor or medical professional to discuss genetic testing options.

Get in touch with DNA Labs India for accurate and reliable genetic testing services.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for KLF8 Gene Mental retardation non-syndromic NGS Genetic DNA Test