Test Name	KISS1R Gene Hypogonadotropic hypogonadism NGS Genetic DNA Test
Test type	General Physician
Pre-test Information	Clinical History of Patient who is going for KISS1R Gene Hypogonadotropic hypogonadism NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with KISS1R Gene Hypogonadotropic hypogonadism NGS Genetic DNA Test gene KISS1R
Report Delivery	3 to 4 Weeks
Components
Price	₹ 20000
Method	NGS Technology

Short Description

NGS genetic DNA test detecets for variant and mutation detection in KISS1R gene for Hypogonadotropic hypogonadism

PreTest Information

Clinical History of Patient who is going for KISS1R Gene Hypogonadotropic hypogonadism NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with KISS1R Gene Hypogonadotropic hypogonadism NGS Genetic DNA Test gene KISS1R

Detail Description

KISS1R Gene Hypogonadotropic Hypogonadism NGS Genetic DNA Test

Introduction

Hypogonadotropic hypogonadism (HH) is a condition that affects the reproductive system of both men and women. It is characterized by a deficiency in the production of gonadotropin-releasing hormone (GnRH), which leads to low levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This, in turn, leads to a decrease in the production of sex hormones such as testosterone and estrogen. HH can be caused by a variety of factors, including genetic mutations. One such genetic mutation that can cause HH is a mutation in the KISS1R gene. The KISS1R gene is responsible for producing a protein called the Kisspeptin receptor, which plays a key role in the regulation of the reproductive system. Mutations in this gene can lead to a disruption in the production of GnRH, resulting in HH.

Symptoms of Hypogonadotropic Hypogonadism

The symptoms of HH can vary depending on the severity of the condition and the age of onset. In males, symptoms may include:

• Delayed puberty
• Decreased muscle mass
• Decreased facial and body hair
• Small testes
• Erectile dysfunction

In females, symptoms may include:

• Delayed puberty
• Lack of breast development
• Infertility
• Absent or irregular menstrual periods

Diagnosis of Hypogonadotropic Hypogonadism

Diagnosis of HH involves a combination of physical exams, blood tests, and imaging studies. Blood tests can be used to measure the levels of LH, FSH, and sex hormones. Imaging studies, such as magnetic resonance imaging (MRI), can be used to evaluate the structure of the hypothalamus and pituitary gland. Genetic testing can also be used to identify mutations in genes such as the KISS1R gene that may be causing HH. Next-generation sequencing (NGS) is a powerful tool for identifying genetic mutations and can provide detailed information about the specific genetic changes that are responsible for the condition.

KISS1R Gene Hypogonadotropic Hypogonadism NGS Genetic DNA Test Cost

The cost of the KISS1R gene hypogonadotropic hypogonadism NGS genetic DNA test in India is approximately INR 20,000. This test is typically covered by health insurance, but it is important to check with your insurance provider to confirm coverage.

Conclusion

Hypogonadotropic hypogonadism is a condition that can have a significant impact on a person's reproductive health. Genetic mutations, such as those in the KISS1R gene, can be responsible for the development of this condition. NGS genetic DNA testing is a powerful tool for identifying these mutations and can provide valuable information for diagnosis and treatment. If you are experiencing symptoms of HH, it is important to speak with your healthcare provider to determine the appropriate diagnostic and treatment options.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for KISS1R Gene Hypogonadotropic hypogonadism NGS Genetic DNA Test