Short Description

NGS genetic DNA test detecets for variant and mutation detection in KHDC3L gene for Hydatidiform mole, recurrent, type 2

PreTest Information

Clinical History of Patient who is going for KHDC3L Gene Hydatidiform mole, recurrent, type 2 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with KHDC3L Gene Hydatidiform mole, recurrent, type 2 NGS Genetic DNA Test gene KHDC3L

Detail Description

Understanding KHDC3L Gene and Hydatidiform Mole: Symptoms, Diagnosis and NGS Genetic DNA Test Cost

Hydatidiform mole is a rare condition that occurs during pregnancy. In this condition, the placenta develops into a mass of abnormal cells that can cause complications for both the mother and the fetus. The KHDC3L gene has been found to play a role in the development of hydatidiform mole, particularly in the recurrent type 2 form of the condition. Here, we’ll take a closer look at hydatidiform mole, the role of the KHDC3L gene, and the importance of NGS genetic DNA testing in diagnosis.

What is Hydatidiform Mole?

Hydatidiform mole, also known as a molar pregnancy, is a rare type of pregnancy in which the placenta develops into a mass of cysts. This condition can occur in any pregnancy but is more likely to occur in women over the age of 35 or under the age of 20. There are two types of hydatidiform mole: complete and partial.

In a complete hydatidiform mole, the egg is fertilized but the embryo does not develop. Instead, the placenta develops into a mass of cysts that look like a bunch of grapes. In a partial hydatidiform mole, the egg is fertilized by two sperm, resulting in an abnormal embryo and placenta.

Hydatidiform mole can cause a number of complications, including vaginal bleeding, high blood pressure, and the development of gestational trophoblastic disease (GTD), a rare type of cancer that affects the cells that form the placenta.

The Role of KHDC3L Gene in Hydatidiform Mole

The KHDC3L gene has been found to play a role in the development of hydatidiform mole, particularly in the recurrent type 2 form of the condition. This gene is involved in the regulation of cell division and growth, which are key processes in the development of the placenta during pregnancy.

When the KHDC3L gene is mutated, it can lead to abnormal cell growth and division in the placenta, resulting in the development of hydatidiform mole. This is particularly true in cases of recurrent hydatidiform mole, where the condition occurs in multiple pregnancies.

Symptoms of Hydatidiform Mole

The symptoms of hydatidiform mole can vary depending on the type and severity of the condition. Some common symptoms include:

• Vaginal bleeding
• Abnormal growth of the uterus
• Nausea and vomiting
• High blood pressure
• Anemia

If you experience any of these symptoms during pregnancy, it is important to speak with your healthcare provider right away.

Diagnosis of Hydatidiform Mole

Hydatidiform mole is typically diagnosed through a combination of physical exams, ultrasounds, and blood tests. During a physical exam, your healthcare provider will check for an enlarged uterus or other signs of pregnancy complications. An ultrasound can help to confirm the diagnosis and determine the type and severity of the condition. Blood tests can be used to measure hormone levels, which can also help to diagnose hydatidiform mole.

NGS Genetic DNA Test Cost

NGS genetic DNA testing is an important tool in the diagnosis of hydatidiform mole, particularly in cases of recurrent type 2. This test can help to identify mutations in the KHDC3L gene that may be contributing to the development of the condition.

The cost of NGS genetic DNA testing for hydatidiform mole can vary depending on the provider and location. In India, the cost of this test is typically around INR 20,000.

Conclusion

Hydatidiform mole is a rare condition that can cause complications during pregnancy. The KHDC3L gene has been found to play a role in the development of this condition, particularly in cases of recurrent type 2. NGS genetic DNA testing is an important tool in the diagnosis of hydatidiform mole and can help to identify mutations in the KHDC3L gene. If you experience symptoms of hydatidiform mole during pregnancy, it is important to speak with your healthcare provider right away.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for KHDC3L Gene Hydatidiform mole, recurrent, type 2 NGS Genetic DNA Test