Short Description

NGS genetic DNA test detecets for variant and mutation detection in ITGAM gene for Systemic lupus erythematosus, susceptibility to

PreTest Information

Clinical History of Patient who is going for ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic DNA Test gene ITGAM

Detail Description

ITGAM Gene and Systemic Lupus Erythematosus: Understanding Susceptibility and Diagnosis through NGS Genetic DNA Test

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organ systems and can cause inflammation and damage to different parts of the body. According to the Lupus Foundation of America, approximately 1.5 million Americans and 5 million people worldwide have lupus.

The exact cause of lupus is not fully understood, but genetic factors are believed to play a role in the development of the disease. One of the genes associated with lupus susceptibility is the ITGAM gene, which codes for a protein called integrin alpha M (CD11b).

The Role of ITGAM Gene in Lupus

The ITGAM gene is located on chromosome 16 and is involved in the immune system's response to infections and foreign substances. The CD11b protein is expressed on the surface of immune cells, including macrophages, dendritic cells, and neutrophils, and helps these cells attach to and engulf foreign particles.

Studies have shown that variations in the ITGAM gene increase the risk of developing lupus. These variations can affect the function of the CD11b protein, leading to abnormal immune responses and inflammation.

NGS Genetic DNA Test for Lupus Diagnosis

Lupus is a complex disease, and its diagnosis can be challenging. The symptoms of lupus can vary widely and can be similar to those of other autoimmune and inflammatory conditions.

NGS (Next Generation Sequencing) Genetic DNA Test is a powerful tool for detecting genetic variations associated with lupus susceptibility, including variations in the ITGAM gene. The test analyzes the patient's DNA sample and identifies variations in specific genes that increase the risk of developing lupus.

The NGS Genetic DNA Test can also help diagnose lupus in patients with unclear symptoms. The test can identify genetic variations that are specific to lupus and distinguish them from other autoimmune and inflammatory conditions.

Cost and Availability of NGS Genetic DNA Test in India

The cost of NGS Genetic DNA Test for lupus diagnosis in India is approximately INR 20,000. The test is available at several DNA labs in India, including DNA Labs India.

DNA Labs India is a leading provider of genetic testing services in India, offering a wide range of DNA tests, including NGS Genetic DNA Test for lupus diagnosis. The lab is equipped with state-of-the-art technology and staffed by experienced geneticists and technicians, ensuring accurate and reliable results.

Conclusion

NGS Genetic DNA Test is a valuable tool for understanding the genetic factors that contribute to lupus susceptibility and for diagnosing the disease. The ITGAM gene is one of the genes associated with lupus susceptibility, and variations in this gene can affect the function of the CD11b protein and lead to abnormal immune responses and inflammation.

DNA Labs India offers NGS Genetic DNA Test for lupus diagnosis at an affordable cost, making it accessible to patients in India. The test can help diagnose lupus in patients with unclear symptoms and provide valuable information for the management and treatment of the disease.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for ITGAM Gene Systemic lupus erythematosus, susceptibility to NGS Genetic DNA Test