Short Description

NGS genetic DNA test detecets for variant and mutation detection in IRF8 gene for Immunodeficiency type 32A, mycobacteriosis, autosomal dominant

PreTest Information

Clinical History of Patient who is going for IRF8 Gene Immunodeficiency type 32A, mycobacteriosis, autosomal dominant NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with IRF8 Gene Immunodeficiency type 32A, mycobacteriosis, autosomal dominant NGS Genetic DNA Test gene IRF8

Detail Description

IRF8 Gene Immunodeficiency Type 32A: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost

IRF8 gene immunodeficiency type 32A is a rare genetic disorder that affects the immune system of individuals. It is caused by mutations in the IRF8 gene, which plays a crucial role in the development and functioning of immune cells. Individuals with this condition are more susceptible to infections caused by mycobacteria, which can lead to mycobacteriosis. This condition is inherited in an autosomal dominant pattern, which means that an affected individual has a 50% chance of passing the mutated gene to their offspring.

Symptoms

The symptoms of IRF8 gene immunodeficiency type 32A vary from individual to individual. Some individuals may experience recurrent infections, while others may have more severe symptoms. The most common symptoms of this condition include:

• Fever
• Cough
• Weight loss
• Sweating at night
• Fatigue

Individuals with this condition may also develop other infections, such as pneumonia, skin infections, and bone infections.

Diagnosis

Diagnosis of IRF8 gene immunodeficiency type 32A is made through genetic testing. Next-generation sequencing (NGS) technology is used to analyze the DNA sequence of the IRF8 gene. This technology can detect mutations in the gene, which can confirm a diagnosis of the condition. Genetic counseling is also recommended for individuals who are diagnosed with this condition, as it can help them understand the inheritance pattern and the risk of passing the mutated gene to their offspring.

NGS Genetic DNA Test Cost

The cost of NGS genetic DNA testing for IRF8 gene immunodeficiency type 32A can vary depending on the testing facility and the specific test that is ordered. In India, the cost of this test is typically around INR 20,000. However, it is important to note that this cost may be covered by insurance in some cases.

Conclusion

IRF8 gene immunodeficiency type 32A is a rare genetic disorder that affects the immune system of individuals. It is caused by mutations in the IRF8 gene, which can lead to mycobacteriosis. Diagnosis of this condition is made through genetic testing using NGS technology. The cost of this test in India is around INR 20,000. Genetic counseling is recommended for individuals who are diagnosed with this condition to help them understand the inheritance pattern and the risk of passing the mutated gene to their offspring.

At DNA Labs India, we offer reliable and accurate NGS genetic DNA testing for IRF8 gene immunodeficiency type 32A. Contact us today to learn more about our testing services.