Short Description

NGS genetic DNA test detecets for variant and mutation detection in IRAK4 gene for Invasive pneumococcal disease, recurrent isolated type 1

PreTest Information

Clinical History of Patient who is going for IRAK4 Gene Invasive pneumococcal disease, recurrent isolated type 1 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with IRAK4 Gene Invasive pneumococcal disease, recurrent isolated type 1 NGS Genetic DNA Test gene IRAK4

Detail Description

Understanding IRAK4 Gene and Invasive Pneumococcal Disease

Invasive pneumococcal disease (IPD) is a serious bacterial infection caused by Streptococcus pneumoniae. It can lead to severe illnesses such as pneumonia, meningitis, and sepsis. Recurrent isolated type 1 IPD is a rare condition that affects individuals who have a genetic predisposition to the disease. One of the genes associated with this condition is the IRAK4 gene. In this blog, we will explore the role of the IRAK4 gene in IPD, its symptoms, diagnosis, and the cost of NGS genetic DNA testing for this condition in India.

The Role of IRAK4 Gene in IPD

The immune system plays a critical role in protecting the body against infections. The IRAK4 gene is involved in the signaling pathway that activates the immune response to bacterial infections. Mutations in this gene can impair the immune system's ability to fight off infections caused by Streptococcus pneumoniae, leading to recurrent isolated type 1 IPD.

Symptoms of Recurrent Isolated Type 1 IPD

The symptoms of recurrent isolated type 1 IPD are similar to those of other types of IPD. These may include:

• Fever
• Cough
• Shortness of breath
• Chest pain
• Stiff neck
• Headache
• Nausea and vomiting

Individuals with recurrent isolated type 1 IPD may experience these symptoms multiple times in their lifetime.

Diagnosis of Recurrent Isolated Type 1 IPD

Diagnosing recurrent isolated type 1 IPD requires a thorough evaluation of the patient's medical history, symptoms, and family history. Genetic testing can also be used to identify mutations in the IRAK4 gene that may be contributing to the disease.

NGS Genetic DNA Test Cost in India

The cost of NGS genetic DNA testing for recurrent isolated type 1 IPD in India is approximately INR 20,000. This test can provide valuable information about an individual's genetic predisposition to the disease, allowing for early detection and management.

Conclusion

Recurrent isolated type 1 IPD is a rare condition that can be caused by mutations in the IRAK4 gene. Understanding the role of this gene in the immune system's response to bacterial infections can help with the early detection and management of the disease. Genetic testing can provide valuable information about an individual's genetic predisposition to the disease, allowing for early intervention. If you have any concerns about your risk for recurrent isolated type 1 IPD, speak to your healthcare provider.