Short Description

SOX-10 plays a critical role in differentiation, maturation & maintenance of schwann cells & melanocytes. Expression of SOX-10 is seen in neural crest derived cells and hence it is positive in nerve sheath tumors, granular cell tumor & melanocytic tumors. It is strongly & diffusely expressed by Spindle cell / Desmoplastic melanoma & thus helps to distinguish Melanoma from scar. All peripheral nerve sheath tumors whether benign or malignant express SOX-10.

PreTest Information

Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Detail Description

IMMUNOHISTOCHEMISTRY SOX-10 Test: Cost, Symptoms, and Diagnosis

IMMUNOHISTOCHEMISTRY SOX-10 Test is a diagnostic test that is used to detect the presence of a protein called SOX-10. This protein is found in cells that produce myelin, which is a fatty substance that covers nerve cells. The test is used to diagnose certain conditions like melanoma, schwannoma, and neurofibroma. In this blog, we will discuss the cost of the test, symptoms, and diagnosis.

The Cost of IMMUNOHISTOCHEMISTRY SOX-10 Test

The cost of the IMMUNOHISTOCHEMISTRY SOX-10 test in India is INR 3500. The cost may vary from one lab to another, but it is usually in this range. It is important to note that this test is not covered by insurance, and the patient will have to pay for it out of pocket.

Symptoms of Conditions Diagnosed by IMMUNOHISTOCHEMISTRY SOX-10 Test

The IMMUNOHISTOCHEMISTRY SOX-10 test is used to diagnose conditions like melanoma, schwannoma, and neurofibroma. Let's take a look at the symptoms of these conditions:

• Melanoma: Melanoma is a type of skin cancer that can develop anywhere on the body. The symptoms of melanoma include a new mole or a change in an existing mole, an asymmetrical mole, a mole with an irregular border, a mole with different colors, and a mole that is larger than 6mm in diameter.
• Schwannoma: Schwannoma is a tumor that develops in the cells that produce myelin. The symptoms of schwannoma include numbness, weakness, tingling, and pain in the affected area. The tumor can also cause a loss of muscle mass and reflexes.
• Neurofibroma: Neurofibroma is a tumor that develops in the nerves and can occur anywhere in the body. The symptoms of neurofibroma include a soft, rubbery lump under the skin, changes in skin color, and pain or tingling in the affected area.

Diagnosis of Conditions Using IMMUNOHISTOCHEMISTRY SOX-10 Test

The IMMUNOHISTOCHEMISTRY SOX-10 test is used to diagnose conditions like melanoma, schwannoma, and neurofibroma. The test is performed on a tissue sample taken from the affected area. The tissue sample is then examined under a microscope to look for the presence of the SOX-10 protein. If the protein is present, it indicates the presence of one of these conditions.

Conclusion

The IMMUNOHISTOCHEMISTRY SOX-10 test is a diagnostic test that is used to detect the presence of the SOX-10 protein. The test is used to diagnose conditions like melanoma, schwannoma, and neurofibroma. The cost of the test in India is INR 3500, and it is not covered by insurance. If you are experiencing any of the symptoms mentioned above, it is important to consult a doctor for diagnosis and treatment.

For more information on the IMMUNOHISTOCHEMISTRY SOX-10 test and other diagnostic tests, contact DNA Labs India.

SOX-10 plays a critical role in differentiation, maturation & maintenance of schwann cells & melanocytes. Expression of SOX-10 is seen in neural crest derived cells and hence it is positive in nerve sheath tumors, granular cell tumor & melanocytic tumors. It is strongly & diffusely expressed by Spindle cell / Desmoplastic melanoma & thus helps to distinguish Melanoma from scar. All peripheral nerve sheath tumors whether benign or malignant express SOX-10.