Short Description

Recent studies have shown that in approximately 70% of patients with primary MN (pMN), the glomerular immune complexes consist of autoantibodies against the podocyte protein M-type phospholipase A2 receptor (PLA2R). There is also evidence that levels of anti-PLA2R autoantibodies correlate well with disease activity and progression and can be used to monitor the disease activity in follow up. It may be noted that results of positive PLA2R staining, though highly suggestive of a Primary membranous nephropathy, should be interpreted in conjunction with other clinical and laboratory parameters, serum PLA2R levels and relevant renal biopsy findings. Absence of staining in renal biopsy or negative serology for PLA2R does not completely exclude Primary membranous nephropathy.

PreTest Information

Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Detail Description

IMMUNOHISTOCHEMISTRY PLA2R Test cost INR:3500 symptoms diagnosis

IMMUNOHISTOCHEMISTRY PLA2R Test is a diagnostic test that helps in the detection of various diseases. At DNA Labs India, we provide the best treatment and care for all your medical conditions.

What is IMMUNOHISTOCHEMISTRY PLA2R Test?

IMMUNOHISTOCHEMISTRY PLA2R Test is a diagnostic test that helps in the detection of various diseases such as glomerulonephritis, lupus nephritis, and membranous nephropathy. It is a blood test that measures the level of PLA2R antibodies in the blood. These antibodies are produced by the immune system in response to certain diseases.

What are the symptoms of IMMUNOHISTOCHEMISTRY PLA2R Test?

The symptoms of IMMUNOHISTOCHEMISTRY PLA2R Test depend on the type of disease that is being detected. Some of the common symptoms include:

• Fatigue
• Swelling in the feet and ankles
• High blood pressure
• Proteinuria (excess protein in the urine)
• Hematuria (blood in the urine)

What is the diagnosis process for IMMUNOHISTOCHEMISTRY PLA2R Test?

The diagnosis process for IMMUNOHISTOCHEMISTRY PLA2R Test involves several steps:

• Physical examination
• Blood test
• Urine test
• Kidney biopsy (in some cases)

What is the cost of IMMUNOHISTOCHEMISTRY PLA2R Test?

The cost of IMMUNOHISTOCHEMISTRY PLA2R Test at DNA Labs India is INR 3500.

Conclusion

IMMUNOHISTOCHEMISTRY PLA2R Test is a diagnostic test that helps in the detection of various diseases. At DNA Labs India, we provide the best treatment and care for all your medical conditions. If you are experiencing any symptoms, it is important to get yourself tested and seek medical attention as soon as possible.

Recent studies have shown that in approximately 70% of patients with primary MN (pMN), the glomerular immune complexes consist of autoantibodies against the podocyte protein M-type phospholipase A2 receptor (PLA2R). There is also evidence that levels of anti-PLA2R autoantibodies correlate well with disease activity and progression and can be used to monitor the disease activity in follow up. It may be noted that results of positive PLA2R staining, though highly suggestive of a Primary membranous nephropathy, should be interpreted in conjunction with other clinical and laboratory parameters, serum PLA2R levels and relevant renal biopsy findings. Absence of staining in renal biopsy or negative serology for PLA2R does not completely exclude Primary membranous nephropathy.