Short Description

p16 expression plays a major role in the evaluation of Cervical Squamous Intraepithelial lesions (SIL) & distinguishing dysplasia from benign mimics. Overexpression is seen in most high risk HPV associated squamous lesions whereas absent / focal weak expression is seen in normal / inflamed / atrophic cervical epithelium. p16 expression has also been seen in non HPV related tumors like High grade serous carcinoma & Atypical uterine smooth muscle tumors like Leiomyosarcomas. Testing of oropharynyngeal squamous cell carcinomas with p16 is also indicated where it serves as an excellent surrogate marker for active HPV.

PreTest Information

Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Detail Description

IMMUNOHISTOCHEMISTRY P16 Test Cost - DNA Labs India

IMMUNOHISTOCHEMISTRY P16 Test is a popular test used for the diagnosis of cervical cancer. This test is offered by DNA Labs India at a cost of INR 3500. In this blog, we will discuss in detail about the symptoms and diagnosis of this test.

What is IMMUNOHISTOCHEMISTRY P16 Test?

IMMUNOHISTOCHEMISTRY P16 Test is a diagnostic test used to detect the presence of abnormal cells in the cervix. This test is also known as p16INK4a immunohistochemistry test. The test is mainly used to diagnose cervical cancer and determine if the cancer is caused by the human papillomavirus (HPV).

Symptoms of Cervical Cancer

• Abnormal vaginal bleeding
• Pain during sexual intercourse
• Pain during urination
• Unusual vaginal discharge
• Lower back pain
• Weight loss

Diagnosis of IMMUNOHISTOCHEMISTRY P16 Test

IMMUNOHISTOCHEMISTRY P16 Test is a simple and quick test that can be done in a laboratory. The test involves taking a small sample of tissue from the cervix and examining it under a microscope. The test looks for the presence of the p16INK4a protein, which is overproduced in cells infected with HPV.

If the test results show the presence of p16INK4a protein, it indicates that the patient has abnormal cells in the cervix and may be at risk of developing cervical cancer. If the test results are negative, it indicates that the patient does not have abnormal cells in the cervix and is not at risk of developing cervical cancer.

Conclusion

IMMUNOHISTOCHEMISTRY P16 Test is an important diagnostic test that can help in the early detection of cervical cancer. The test is offered by DNA Labs India at a cost of INR 3500. If you are experiencing any of the symptoms of cervical cancer, it is important to get yourself tested. Book your test today and take a step towards a healthier life.

p16 expression plays a major role in the evaluation of Cervical Squamous Intraepithelial lesions (SIL) & distinguishing dysplasia from benign mimics. Overexpression is seen in most high risk HPV associated squamous lesions whereas absent / focal weak expression is seen in normal / inflamed / atrophic cervical epithelium. p16 expression has also been seen in non HPV related tumors like High grade serous carcinoma & Atypical uterine smooth muscle tumors like Leiomyosarcomas. Testing of oropharynyngeal squamous cell carcinomas with p16 is also indicated where it serves as an excellent surrogate marker for active HPV.