Short Description

Mucins play important roles in the protection of epithelial cells and have been implicated in epithelial renewal and differentiation. MUC4 is expressed in the cytoplasm and membrane of respiratory, gastrointestinal, cervical and prostatic epithelial cells. Overexpression of MUC4 has been observed in many carcinomas. It has been shown to be useful for the distinction between Sarcomatoid carcinoma (often expressed) versus Sarcomatoid mesothelioma (usually negative).

PreTest Information

Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Detail Description

What is Immunohistochemistry MUC4 Test and its Cost?

Immunohistochemistry (IHC) is a diagnostic process that utilizes antibodies to identify specific proteins in tissue samples. It is a valuable tool for diagnosing various diseases, including cancer, and is commonly used in pathological examinations. MUC4 is a protein that is overexpressed in several types of cancer, including pancreatic, ovarian, and breast cancer. The Immunohistochemistry MUC4 Test is used to identify MUC4 protein expression in tissue samples.

What are the Symptoms of MUC4 Overexpression?

The symptoms of MUC4 overexpression depend on the type of cancer. In pancreatic cancer, patients may experience abdominal pain, weight loss, and jaundice. In ovarian cancer, symptoms may include abdominal swelling, pain, and bloating. Breast cancer may present with a lump or thickening in the breast tissue. However, these symptoms are not specific to MUC4 overexpression and may also be present in other conditions.

How is MUC4 Overexpression Diagnosed?

MUC4 overexpression is diagnosed through a tissue biopsy. The biopsy sample is examined using Immunohistochemistry to detect MUC4 protein expression. The test can also determine the extent of MUC4 overexpression, which can help in determining the stage of cancer and devising an appropriate treatment plan.

What is the Cost of Immunohistochemistry MUC4 Test?

The cost of Immunohistochemistry MUC4 Test in India varies depending on the location and the laboratory conducting the test. On average, the test costs around INR 3500. However, the cost may differ based on the type of tissue sample, the complexity of the test, and the location of the laboratory.

Conclusion

Immunohistochemistry MUC4 Test is a valuable diagnostic tool used to identify MUC4 protein expression in tissue samples. The test is commonly used in the diagnosis of several types of cancer, including pancreatic, ovarian, and breast cancer. The cost of the test varies depending on the location and laboratory conducting the test, and it is essential to consult with a medical professional to determine if the test is necessary and where to get it done.

If you are looking to get the Immunohistochemistry MUC4 Test done in India, DNA Labs India is a reliable and trustworthy laboratory that offers the test at an affordable cost. Contact DNA Labs India today to learn more about the test and schedule an appointment.

Remember, early detection is the key to successful treatment and recovery. Don't wait until it's too late, get tested today!

Mucins play important roles in the protection of epithelial cells and have been implicated in epithelial renewal and differentiation. MUC4 is expressed in the cytoplasm and membrane of respiratory, gastrointestinal, cervical and prostatic epithelial cells. Overexpression of MUC4 has been observed in many carcinomas. It has been shown to be useful for the distinction between Sarcomatoid carcinoma (often expressed) versus Sarcomatoid mesothelioma (usually negative).