IMMUNOHISTOCHEMISTRY (IHC) is a diagnostic technique that helps in identifying specific proteins in tissues using antibodies. It is commonly used in cancer diagnosis and research. One of the tests that use IHC is the MDM2 Test, which helps in the diagnosis of certain types of cancers.
What is the MDM2 Test?
The MDM2 Test is an IHC test that detects the overexpression of the MDM2 protein in cancer cells. MDM2 is a protein that regulates cell growth and division. Overexpression of MDM2 can lead to uncontrolled cell growth, which is a hallmark of cancer.
What are the symptoms of cancer?
The symptoms of cancer can vary depending on the type and stage of cancer. Some common symptoms include:
- Unexplained weight loss
- Fatigue
- Persistent pain
- Lumps or growths on the body
- Changes in bowel or bladder habits
- Difficulty swallowing
- Hoarseness or a persistent cough
- Unusual bleeding or discharge
If you are experiencing any of these symptoms, it is important to consult a doctor for proper diagnosis and treatment.
How is the MDM2 Test used in cancer diagnosis?
The MDM2 Test is used to diagnose certain types of cancer, including liposarcoma, dedifferentiated chondrosarcoma, and atypical lipomatous tumor. These types of cancer are characterized by the overexpression of MDM2.
The MDM2 Test involves taking a tissue sample from the affected area and staining it with antibodies that specifically target MDM2. The stained tissue is then examined under a microscope to determine if there is an overexpression of MDM2.
What is the cost of the MDM2 Test in India?
The cost of the MDM2 Test in India can vary depending on the laboratory and location. At DNA Labs India, we offer the MDM2 Test for INR 3500. We are committed to providing affordable and accurate diagnostics services to our patients.
If you are experiencing symptoms of cancer or have been diagnosed with cancer, it is important to seek timely and appropriate medical care. The MDM2 Test can help in the diagnosis and treatment of certain types of cancer, and DNA Labs India is here to provide you with reliable and affordable diagnostics services.
MDM2 overexpression is frequently seen in Low grade osteosarcomas & is usually accompanied by overexpression of CDK4. Majority of Parosteal & Central low grade osteosarcomas express MDM2 with moderate or strong intensity whereas the staining is negative in primary conventional High grade osteosarcomas. It is also expressed by extra-skeletal Soft tissue osteosarcomas, heterologous osteosarcomatous differentiation in Dedifferentiated liposarcomas & MPNST.