Short Description

Amyloidosis, often a multiorgan disease is characterized by deposition of Congophilic fibrillary material with the affected organs composed of randomly oriented non- branching fibrils measuring about 7-11 nm in diameter. Among the commonly prevalent sub- types, AL amyloidosis is derived from immunoglobulin light chains and AA amyloid from serum amyloid A protein (AA). The less common variants include those derived from fibrinogen (AFib), transthyretin (ATTR), lysozyme (ALys), and apolipoproteins AI or AII (AApoAI, AApoAII).Amyloid deposits composed of leukocyte chemotactic factor 2 (LECT2) are described recently and in some series are found to be the third most common amyloid subtypes after AA and AL amyloid. Leukocyte cell-derived chemotaxin 2 (LECT2) was originally isolated and characterized from culture media of PHA-activated human T-cell leukemia cells as part of studies to identify chemotactic factors important in the pathophysiology of neoplasia. Although the original characterization of LECT2 proved to be of bovine origin from the fetal calf serum used in media, these studies led to the cloning and structural characterization of the human analog. The protein was independently characterized from fetal bovine cartilage and named chondromodulin II.The human LECT2 gene is localized to chromosome 5 (5q31.1ƒ??q32) and consists of four exons and three introns. The gene codes for 151 amino acids (MW 16 376 Da) including an 18 amino acid signal peptide. The secreted protein has 133 residues.

PreTest Information

Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Detail Description

IMMUNOHISTOCHEMISTRY LECT2 Test: Cost, Symptoms, Diagnosis

IMMUNOHISTOCHEMISTRY LECT2 Test is a diagnostic tool that helps in detecting the presence of LECT2 protein in the body. The test is performed using immunohistochemistry, which is a technique that uses antibodies to detect specific proteins in tissue samples.

Cost of IMMUNOHISTOCHEMISTRY LECT2 Test

The cost of the IMMUNOHISTOCHEMISTRY LECT2 Test in India is around INR 1872. The cost may vary depending on the location and the laboratory where the test is performed. It is always advisable to check the cost of the test with the laboratory before getting the test done.

Symptoms of LECT2 Protein Presence

LECT2 protein is mainly produced by the liver and is involved in various physiological processes in the body. The presence of LECT2 protein in the body can indicate certain health conditions. Some of the symptoms that may indicate the presence of LECT2 protein in the body are:

• Abdominal pain
• Jaundice
• Itching
• Fatigue
• Loss of appetite

Diagnosis of LECT2 Protein Presence

The diagnosis of LECT2 protein presence is done through the IMMUNOHISTOCHEMISTRY LECT2 Test. The test is performed on a tissue sample obtained from the liver. The tissue sample is examined under a microscope, and antibodies are used to detect the presence of LECT2 protein.

If the test indicates the presence of LECT2 protein in the body, further tests may be required to determine the underlying health condition. The doctor may recommend additional blood tests, imaging tests, or a liver biopsy to determine the cause of the symptoms.

Conclusion

The IMMUNOHISTOCHEMISTRY LECT2 Test is an important diagnostic tool that can help in detecting the presence of LECT2 protein in the body. The test is relatively affordable and can provide vital information that can help in the diagnosis of certain health conditions. If you are experiencing any of the symptoms mentioned above, it is advisable to consult a doctor and get the IMMUNOHISTOCHEMISTRY LECT2 Test done.

At DNA Labs India, we offer a wide range of diagnostic tests, including the IMMUNOHISTOCHEMISTRY LECT2 Test. Our team of experienced and qualified professionals uses state-of-the-art equipment to provide accurate and reliable test results. Contact us today to learn more about our services.