Short Description

Cyclin-D1 is one of the members of cell cycle proteins that drives the transition between G0 & G1 phase. In normal tissues, basal epithelial cells, endothelial cells & stromal cells are often Cyclin-D1 positive. Due to translocation involving Cyclin-D1 gene & IgH, majority of Mantle cell Lymphomas overexpress Cyclin-D1. This is a useful feature in the classification of Low grade B cell lymphomas.

PreTest Information

Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Detail Description

IMMUNOHISTOCHEMISTRY CYCLIN-D1 Test: Symptoms, Diagnosis, and Cost

IMMUNOHISTOCHEMISTRY CYCLIN-D1 is a diagnostic test that helps in identifying the presence of cyclin D1, a protein that plays a crucial role in cell cycle regulation. The test is used for various types of cancer diagnosis, including breast cancer, lymphoma, and head and neck cancer. DNA Labs India offers the test at a cost of INR 3500.

Symptoms

The symptoms of cancer vary depending on the type and stage of cancer. However, some of the common symptoms that may indicate the need for an IMMUNOHISTOCHEMISTRY CYCLIN-D1 test include:

• Lumps or masses in the breast
• Swollen lymph nodes
• Difficulty swallowing or breathing
• Unexplained weight loss
• Chronic fatigue
• Persistent cough or hoarseness

Diagnosis

The IMMUNOHISTOCHEMISTRY CYCLIN-D1 test is a type of immunohistochemistry (IHC) test, which uses antibodies to detect specific proteins in tissue samples. The test is often used in combination with other diagnostic tests, such as a biopsy or imaging tests, to confirm a cancer diagnosis.

During the test, a small tissue sample is taken from the affected area, which is then analyzed under a microscope. The tissue is stained with antibodies that specifically bind to cyclin D1, which can then be visualized under a microscope. The presence of cyclin D1 indicates the presence of cancer cells.

Cost

The IMMUNOHISTOCHEMISTRY CYCLIN-D1 test cost varies depending on the laboratory and location. DNA Labs India offers the test at a cost of INR 3500. The cost of the test may be covered by insurance, but it is important to check with your insurance provider before undergoing the test.

Conclusion

The IMMUNOHISTOCHEMISTRY CYCLIN-D1 test is a valuable diagnostic tool for detecting various types of cancer. If you are experiencing any of the symptoms mentioned above, it is important to consult a doctor and undergo the necessary diagnostic tests to ensure early detection and treatment of cancer. DNA Labs India offers the test at an affordable cost, making it accessible to all those who require it.

Cyclin-D1 is one of the members of cell cycle proteins that drives the transition between G0 & G1 phase. In normal tissues, basal epithelial cells, endothelial cells & stromal cells are often Cyclin-D1 positive. Due to translocation involving Cyclin-D1 gene & IgH, majority of Mantle cell Lymphomas overexpress Cyclin-D1. This is a useful feature in the classification of Low grade B cell lymphomas.