Short Description

CDK-4 (Cyclin dependent kinase-4) is one of the proteins involved with cell cycle progression and is encoded by a gene at chromosome 12q13. It is overexpressed in cases of Well differentiated liposarcoma & Dedifferentiated liposarcoma. Benign lipomatous lesions, Pleomorphic liposarcoma & Myxoid liposarcoma are negative for CDK4. The best diagnostic use of this marker is to distinguish between Dedifferentiated liposarcomas from High grade sarcomas.

PreTest Information

Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Detail Description

IMMUNOHISTOCHEMISTRY CDK-4 Test: Cost, Symptoms and Diagnosis

IMMUNOHISTOCHEMISTRY CDK-4 test is a diagnostic test that is used to detect the presence of a protein called Cyclin-Dependent Kinase 4 (CDK-4) in the body. This protein is involved in the regulation of cell growth and division, and abnormalities in its expression can lead to the development of various types of cancers.

Cost of IMMUNOHISTOCHEMISTRY CDK-4 Test

The cost of IMMUNOHISTOCHEMISTRY CDK-4 test in India is around INR 3000. However, the cost may vary depending on the location of the laboratory and other factors.

Symptoms of CDK-4 Abnormalities

Abnormalities in the expression of CDK-4 can lead to the development of various types of cancers, including:

• Melanoma
• Breast Cancer
• Glioma
• Sarcoma
• Lung Cancer

The symptoms of these cancers may vary depending on their location and severity. Some common symptoms include:

• Unexplained weight loss
• Fatigue
• Persistent pain
• Changes in skin texture or color
• Difficulty breathing

Diagnosis of CDK-4 Abnormalities

The diagnosis of CDK-4 abnormalities involves various tests, including the IMMUNOHISTOCHEMISTRY CDK-4 test. Other tests that may be used to diagnose cancer include:

• Biopsy
• Blood tests
• Imaging tests (X-rays, CT scans, MRI scans)

If cancer is diagnosed, further tests may be performed to determine the stage and extent of the cancer.

Conclusion

The IMMUNOHISTOCHEMISTRY CDK-4 test is an important diagnostic tool for detecting abnormalities in the expression of CDK-4, which can lead to the development of various types of cancers. If you experience any symptoms or have a family history of cancer, it is important to consult a healthcare professional for proper diagnosis and treatment.

At DNA Labs India, we offer a range of diagnostic tests, including the IMMUNOHISTOCHEMISTRY CDK-4 test, to help patients get timely and accurate diagnoses. Contact us today to learn more.

CDK-4 (Cyclin dependent kinase-4) is one of the proteins involved with cell cycle progression and is encoded by a gene at chromosome 12q13. It is overexpressed in cases of Well differentiated liposarcoma & Dedifferentiated liposarcoma. Benign lipomatous lesions, Pleomorphic liposarcoma & Myxoid liposarcoma are negative for CDK4. The best diagnostic use of this marker is to distinguish between Dedifferentiated liposarcomas from High grade sarcomas.