Short Description

CD99 is useful in the differential diagnosis of Small round cell tumor especially Ewing Sarcoma/PNET. It is strongly expressed in Ewing sarcoma / Primitive neuroectodermal tumor, distinguishing it from other Small round blue cell tumors of childhood and adolescence.

PreTest Information

Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Detail Description

IMMUNOHISTOCHEMISTRY CD99 (MIC-2) Test: Cost, Symptoms, and Diagnosis

IMMUNOHISTOCHEMISTRY (IHC) is a type of laboratory test that helps diagnose diseases by detecting specific proteins in tissue samples. One of the tests included in IHC is the CD99 (MIC-2) test, which is used to detect the presence of a protein called CD99 in the tissue sample. Here's everything you need to know about the CD99 (MIC-2) test, including its cost, symptoms, and diagnosis.

What is CD99 (MIC-2)?

CD99 (MIC-2) is a protein that is found in most cells in the body. It is particularly abundant in cells that make up the immune system, such as T-cells and B-cells. CD99 is also found in some types of cancer cells, including Ewing's sarcoma, a rare type of bone cancer that mostly affects children and young adults.

What is the CD99 (MIC-2) test?

The CD99 (MIC-2) test is a type of IHC test that is used to detect the presence of CD99 protein in a tissue sample. The test involves staining the tissue sample with a special dye that binds to CD99 protein. If the tissue sample contains CD99 protein, it will appear as a brown color under a microscope.

What are the symptoms of CD99 (MIC-2) protein overexpression?

CD99 (MIC-2) protein overexpression is associated with Ewing's sarcoma, a rare type of bone cancer that mostly affects children and young adults. The symptoms of Ewing's sarcoma may include:

• Pain and swelling in the affected area
• Fever
• Fatigue
• Weight loss

How is the CD99 (MIC-2) test performed?

The CD99 (MIC-2) test is performed on a tissue sample that is obtained through a biopsy or surgical procedure. The tissue sample is then sent to a laboratory, where it is analyzed using the IHC technique. The test results are usually available within a few days.

What is the cost of the CD99 (MIC-2) test?

The cost of the CD99 (MIC-2) test in India is around INR 3000. However, the cost may vary depending on the location and the laboratory that performs the test.

Conclusion

The CD99 (MIC-2) test is an important diagnostic tool that can help detect the presence of CD99 protein in tissue samples. This test is particularly useful in diagnosing Ewing's sarcoma, a rare type of bone cancer that mostly affects children and young adults. If you are experiencing symptoms of Ewing's sarcoma, it is important to talk to your doctor and get a proper diagnosis.

CD99 is useful in the differential diagnosis of Small round cell tumor especially Ewing Sarcoma/PNET. It is strongly expressed in Ewing sarcoma / Primitive neuroectodermal tumor, distinguishing it from other Small round blue cell tumors of childhood and adolescence.