Short Description

C4d is important in the evaluation of renal transplant biopsies as a marker of Antibody mediated rejection.

PreTest Information

Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Detail Description

Understanding C4d Test in Immunohistochemistry: Cost, Symptoms, and Diagnosis

Immunohistochemistry (IHC) is an important diagnostic tool used in pathology and research labs to identify specific antigens in tissue samples. One such test is the C4d test, which measures the presence of the C4d protein in tissue samples. C4d is a marker of complement activation and is useful in the diagnosis of various autoimmune disorders, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and glomerulonephritis.

What is the C4d Test and How is it Performed?

The C4d test is a type of IHC test that uses specific antibodies to detect the presence of C4d in tissue samples. These samples can be collected through a biopsy or surgical procedure. The sample is then processed in a laboratory where it is stained with the C4d antibody. If C4d is present, it will bind with the antibody, producing a visible color change.

What are the Symptoms of Diseases Detected by C4d Test?

The C4d test is used to diagnose autoimmune disorders, which can have a wide range of symptoms. Some of the common symptoms associated with autoimmune disorders include:

• Fatigue
• Joint pain and stiffness
• Swelling in the joints
• Skin rashes
• Fevers
• Weight loss
• Shortness of breath
• Abdominal pain

How is the C4d Test Used in Diagnosis?

The C4d test is used as a diagnostic tool to confirm the presence of autoimmune disorders. When used in conjunction with other tests, such as the antinuclear antibody (ANA) test, it can help identify specific autoimmune disorders. For example, if a patient has a positive ANA test and a positive C4d test, it may indicate a diagnosis of SLE.

What is the Cost of C4d Test in India?

The cost of the C4d test in India can vary depending on the laboratory and location. On average, the cost of the test ranges from INR 3500 to INR 5000. However, it is important to note that the cost of the test may be covered by insurance, depending on the patient's policy.

Conclusion

The C4d test is an important diagnostic tool used in the diagnosis of autoimmune disorders. It is a type of IHC test that measures the presence of the C4d protein in tissue samples. The test is used in conjunction with other tests to confirm the presence of specific autoimmune disorders. The cost of the test in India can vary, but it is an essential test for patients experiencing symptoms of autoimmune disorders.

For more information on the C4d test and other IHC tests, please contact DNA Labs India.

C4d is important in the evaluation of renal transplant biopsies as a marker of Antibody mediated rejection.