Short Description

Bisulfite sequencing library preparation, 2x150 PE Illumina Hiseq sequencing to generate 30GB (10X) data. Alignment of quality filtered reads onto the reference genome and genome wide methylation profiling. Annotation and functional annotation of differentially methylated regions

PreTest Information

Detail Description

Human Bisulfite Sequencing and Analysis Cost INR 120000: Symptoms and Diagnosis

DNA Labs India offers a wide range of DNA testing services, including human bisulfite sequencing and analysis. This advanced technique is used to analyze DNA methylation patterns, which play a critical role in the regulation of gene expression. By identifying changes in DNA methylation patterns, human bisulfite sequencing and analysis can be used to diagnose a variety of genetic disorders and diseases.

What is DNA Methylation?

DNA methylation is the process by which a methyl group is added to the cytosine base of a DNA molecule. This modification can alter the expression of genes and is essential for normal development and cellular function. Aberrant DNA methylation patterns have been linked to a wide range of diseases, including cancer, neurological disorders, and cardiovascular disease.

What is Human Bisulfite Sequencing and Analysis?

Human bisulfite sequencing and analysis is a technique used to map DNA methylation patterns. This technique involves treating DNA with sodium bisulfite, which converts unmethylated cytosine residues to uracil, while leaving methylated cytosine residues intact. The DNA is then sequenced, and the resulting data is analyzed to identify changes in methylation patterns.

What are the Symptoms of Diseases Detected by Human Bisulfite Sequencing and Analysis?

The symptoms of diseases detected by human bisulfite sequencing and analysis can vary widely depending on the specific disorder. Some common symptoms include:

• Developmental delays
• Mental retardation
• Neurological symptoms, such as seizures and tremors
• Increased risk of cancer
• Cardiovascular disease

How is Human Bisulfite Sequencing and Analysis Used for Diagnosis?

Human bisulfite sequencing and analysis can be used to diagnose a variety of genetic disorders and diseases. This technique is particularly useful for identifying changes in DNA methylation patterns that are associated with specific diseases. By analyzing these patterns, doctors can make an accurate diagnosis and develop an appropriate treatment plan.

What is the Cost of Human Bisulfite Sequencing and Analysis?

The cost of human bisulfite sequencing and analysis at DNA Labs India is INR 120000. This cost includes sample collection, processing, and analysis, as well as a detailed report of the results. Patients can expect to receive their results within 2-3 weeks of sample collection.

Conclusion

Human bisulfite sequencing and analysis is a powerful tool for diagnosing genetic disorders and diseases. This advanced technique can identify changes in DNA methylation patterns that are associated with specific conditions, allowing doctors to make an accurate diagnosis and develop an appropriate treatment plan. If you are concerned about a genetic disorder or disease, contact DNA Labs India to learn more about human bisulfite sequencing and analysis.

For more information, please visit our website at https://dnalabsindia.com