Short Description

NGS genetic DNA test detecets for variant and mutation detection in HRAS gene for Costello syndrome

PreTest Information

Clinical History of Patient who is going for HRAS Gene Costello syndrome NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with HRAS Gene Costello syndrome NGS Genetic DNA Test gene HRAS

Detail Description

HRAS Gene Costello Syndrome NGS Genetic DNA Test Cost - DNA Labs India

Costello syndrome is a rare genetic disorder that affects many parts of the body. It is caused by mutations in the HRAS gene, which provides instructions for making a protein that is involved in signaling pathways that regulate cell growth and division.

Costello syndrome is characterized by delayed development and intellectual disability, loose and wrinkled skin, distinctive facial features, and an increased risk of certain cancers. It can also cause heart abnormalities, skeletal abnormalities, and other health problems.

NGS Genetic DNA Test Cost for HRAS Gene Costello Syndrome

The most reliable way to diagnose Costello syndrome is through genetic testing. DNA Labs India offers an NGS genetic DNA test for HRAS gene mutations that can cause Costello syndrome. The cost of this test is INR 20,000.

This test analyzes the DNA sequence of the HRAS gene to detect mutations that are known to cause Costello syndrome. If a mutation is found, it confirms a diagnosis of Costello syndrome. If no mutation is found, it can rule out Costello syndrome as a possible diagnosis.

Symptoms of Costello Syndrome

The symptoms of Costello syndrome vary widely, but some of the most common symptoms include:

• Delayed development and intellectual disability
• Distinctive facial features, such as a wide mouth and thick lips
• Loose and wrinkled skin
• Short stature
• Heart abnormalities
• Skeletal abnormalities
• Increased risk of certain cancers

Other symptoms may include vision and hearing problems, feeding difficulties, and seizures.

Diagnosis of Costello Syndrome

Diagnosing Costello syndrome can be challenging because its symptoms are so varied and can overlap with other conditions. In addition to genetic testing, doctors may use a variety of other tests and evaluations to diagnose Costello syndrome, including:

• Physical examination to look for characteristic features of Costello syndrome
• Developmental assessment to evaluate developmental delays and intellectual disability
• Heart and other imaging tests to identify any abnormalities
• Biopsy or other tests to check for cancer

If you or a loved one is experiencing symptoms of Costello syndrome, it is important to speak with a doctor or genetic counselor to discuss testing options and develop an appropriate treatment plan.

At DNA Labs India, we are committed to providing accurate and reliable genetic testing services to help diagnose and manage a wide range of genetic disorders. Contact us today to learn more about our NGS genetic DNA test for HRAS gene mutations that cause Costello syndrome.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for HRAS Gene Costello syndrome NGS Genetic DNA Test