Short Description

NGS genetic DNA test detecets for variant and mutation detection in HNF4A gene for Maturity-onset diabetes of the young type 1

PreTest Information

Clinical History of Patient who is going for HNF4A Gene Maturity-onset diabetes of the young type 1 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Maturity-onset diabetes of the young type 1

Detail Description

HNF4A Gene Maturity-onset diabetes of the young type 1 NGS Genetic DNA Test

HNF4A (hepatocyte nuclear factor 4 alpha) gene mutations are responsible for maturity-onset diabetes of the young type 1 (MODY1), a rare form of diabetes that affects young adults. The HNF4A gene is responsible for producing a protein that regulates the expression of genes involved in glucose metabolism.

MODY1 is inherited in an autosomal dominant manner, which means that an individual only needs to inherit one copy of the mutated gene from one parent to develop the condition. The symptoms of MODY1 are similar to those of type 1 and type 2 diabetes and include increased thirst, frequent urination, and high blood sugar levels.

Symptoms of MODY1

The symptoms of MODY1 are similar to those of type 1 and type 2 diabetes, including:

• Increased thirst
• Frequent urination
• High blood sugar levels
• Blurred vision
• Fatigue
• Weight loss

MODY1 typically affects young adults, and symptoms can develop as early as adolescence.

Diagnosis of MODY1

MODY1 is diagnosed through genetic testing. A genetic test can identify mutations in the HNF4A gene that are responsible for the condition.

The genetic test for MODY1 is a next-generation sequencing (NGS) test. NGS is a high-throughput DNA sequencing technology that allows for the sequencing of multiple genes at once.

Cost of MODY1 Genetic DNA Test

The cost of the MODY1 genetic DNA test in India is INR 20,000. The test can be performed at DNA Labs India, a leading provider of genetic testing services in the country.

Conclusion

MODY1 is a rare form of diabetes that affects young adults. It is caused by mutations in the HNF4A gene and is inherited in an autosomal dominant manner. Genetic testing is the most accurate way to diagnose MODY1, and the cost of the genetic DNA test is INR 20,000 in India.

If you or someone you know is experiencing symptoms of MODY1, it is important to seek medical attention and consider genetic testing to confirm the diagnosis.

For more information on genetic testing and other DNA-related services, visit DNA Labs India.