Short Description

This assay is used for the detection of pre & post transplantation HLA antibodies in solid organ transplant recipients and in unmatched Bone marrow transplants. It detects antibodies against HLA antigens including HLA- A, B, C, DR, DQA1, DQB1, DPA1 and DPB1.

PreTest Information

Give brief clinical history.

Detail Description

HLA Single Antigen Bead Assay for Class I & II IgG Antibodies DSA-SAB Class I & II Test

HLA Single Antigen Bead Assay for Class I & II IgG Antibodies DSA-SAB Class I & II Test is a laboratory test that is used to determine the presence of specific antibodies in the blood that may indicate a risk of organ rejection in transplant patients. This test is performed using a technique called flow cytometry, which allows for the simultaneous analysis of multiple antigens in a single sample.

What is HLA?

HLA stands for Human Leukocyte Antigen. These are proteins that are found on the surface of almost all cells in the body. The immune system uses these proteins to identify which cells belong to the body and which do not. HLA proteins are highly variable from person to person, which is why organ transplants can be difficult to match.

What is the purpose of the HLA Single Antigen Bead Assay for Class I & II IgG Antibodies DSA-SAB Class I & II Test?

The purpose of this test is to determine whether a transplant patient has developed antibodies against specific HLA proteins. If a patient has developed these antibodies, it may indicate that their immune system is recognizing the transplanted organ as foreign and may attack it. This can lead to organ rejection.

What are the symptoms of organ rejection?

The symptoms of organ rejection can vary depending on the organ that was transplanted. However, common symptoms include fever, chills, fatigue, pain or tenderness over the transplant site, decreased urine output, and flu-like symptoms.

How is organ rejection diagnosed?

Organ rejection is usually diagnosed through a combination of blood tests and imaging studies. The HLA Single Antigen Bead Assay for Class I & II IgG Antibodies DSA-SAB Class I & II Test is just one of the many tests that may be used to diagnose organ rejection.

What is the cost of the HLA Single Antigen Bead Assay for Class I & II IgG Antibodies DSA-SAB Class I & II Test?

The cost of the HLA Single Antigen Bead Assay for Class I & II IgG Antibodies DSA-SAB Class I & II Test in India is INR 50,000.

Conclusion

The HLA Single Antigen Bead Assay for Class I & II IgG Antibodies DSA-SAB Class I & II Test is an important tool in the management of transplant patients. By identifying the presence of specific antibodies, doctors can take steps to prevent organ rejection and ensure the long-term success of the transplant. If you are a transplant patient, talk to your doctor about whether this test may be right for you.

This assay is used for the detection of pre & post transplantation HLA antibodies in solid organ transplant recipients and in unmatched Bone marrow transplants. It detects antibodies against HLA antigens including HLA- A, B, C, DR, DQA1, DQB1, DPA1 and DPB1.