Short Description

High PRA is associated with delayed graft function, high incidence of acute rejection and short graft survival.

PreTest Information

Collect specimen preferably 48 hours after dialysis. Provide brief clinical history.

Detail Description

HLA - PANEL REACTIVE IgG ANTIBODIES (PRA) CLASS I QUANTITATIVE Test

HLA - Panel Reactive IgG Antibodies (PRA) Class I Quantitative Test is a diagnostic test that helps in determining the presence of antibodies against Human Leukocyte Antigen (HLA) in the blood. The HLA system is responsible for identifying foreign substances or antigens in the body and triggering an immune response. However, sometimes the body produces antibodies against its own HLA, which can lead to various autoimmune diseases.

The HLA - PRA Class I Quantitative test measures the amount of IgG antibodies present in the blood against HLA Class I antigens. The test is used to determine the compatibility of organ donors and recipients, especially in kidney transplants. A high PRA value indicates that the recipient has a high risk of rejecting the transplanted organ due to the presence of antibodies in their blood.

Symptoms

There are no specific symptoms associated with having high PRA values. However, in the case of kidney transplant recipients, high PRA values can increase the risk of organ rejection and can cause complications such as fever, pain, swelling, and decreased urine output.

Diagnosis

HLA - Panel Reactive IgG Antibodies (PRA) Class I Quantitative Test is a blood test that is performed in a laboratory. The test involves taking a blood sample from the patient and analyzing it for the presence of HLA antibodies. If the test results show a high PRA value, it indicates that the patient has a high risk of rejecting the transplanted organ.

Test Cost

The cost of the HLA - Panel Reactive IgG Antibodies (PRA) Class I Quantitative Test in India is approximately INR 15,000. However, the cost may vary depending on the location and the laboratory where the test is performed.

Conclusion

The HLA - Panel Reactive IgG Antibodies (PRA) Class I Quantitative Test is an important diagnostic tool for determining the compatibility of organ donors and recipients, especially in kidney transplants. A high PRA value indicates a high risk of organ rejection, and measures can be taken to minimize this risk. If you are a kidney transplant recipient or a potential donor, it is recommended that you undergo this test to ensure the success of the transplant procedure.

At DNA Labs India, we offer a wide range of diagnostic tests, including the HLA - Panel Reactive IgG Antibodies (PRA) Class I Quantitative Test. Our state-of-the-art laboratories and experienced technicians ensure accurate and timely results. Contact us today to book your appointment.

High PRA is associated with delayed graft function, high incidence of acute rejection and short graft survival.