Short Description

HLA-DRB1*1501 Genotyping (Multiple Sclerosis) is performed using Sanger Sequencing methodology. Sample that have to be given is Peripheral blood in EDTA Vacutainer (2ml) for this test. You can expect results in 7-10 days

PreTest Information

HLA-DRB1*1501 Genotyping (Multiple Sclerosis) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.

Detail Description

HLA-DRB1*1501 Genotyping (Multiple Sclerosis): Cost, Symptoms and Diagnosis

Multiple Sclerosis (MS) is a chronic autoimmune disorder that affects the central nervous system. It occurs when the immune system attacks the myelin sheath, a protective covering that surrounds nerve fibers, leading to inflammation and damage. MS can cause a range of symptoms, including vision problems, muscle weakness, and difficulty with coordination and balance.

HLA-DRB1*1501 is a gene that has been associated with an increased risk of developing MS. This gene is involved in the immune system and plays a role in the body's ability to recognize and fight off infections. Research has shown that individuals who carry this gene variant are more likely to develop MS.

HLA-DRB1*1501 Genotyping

HLA-DRB1*1501 genotyping is a test that can identify whether an individual carries the HLA-DRB1*1501 gene variant. This test involves analyzing a sample of DNA, usually collected through a blood sample or cheek swab, to determine the presence or absence of the gene variant.

HLA-DRB1*1501 genotyping can be useful for individuals who have a family history of MS or who are experiencing symptoms of the disease. Knowing whether an individual carries the gene variant can help with early diagnosis and treatment, as well as provide information about the individual's risk of developing MS in the future.

Cost of HLA-DRB1*1501 Genotyping

The cost of HLA-DRB1*1501 genotyping can vary depending on the laboratory and location. At DNA Labs India, the cost of this test is INR 5250. This cost includes the collection of the DNA sample, the analysis of the sample, and a report of the results.

Symptoms of Multiple Sclerosis

The symptoms of MS can vary greatly from person to person, and can also depend on the location and severity of the damage to the central nervous system. Some common symptoms of MS include:

• Vision problems, such as double vision or blurred vision
• Muscle weakness or stiffness
• Numbness or tingling in the limbs
• Difficulty with coordination and balance
• Fatigue
• Cognitive problems, such as difficulty with memory or concentration

MS symptoms can come and go, and can also vary in severity. Some individuals may experience only mild symptoms, while others may experience more severe symptoms that can significantly impact their daily life.

Diagnosis of Multiple Sclerosis

Diagnosing MS can be challenging, as there is no single test that can definitively identify the disease. Instead, a diagnosis is typically made based on a combination of symptoms, medical history, and diagnostic tests.

Some common diagnostic tests for MS include:

• Magnetic resonance imaging (MRI) to detect areas of inflammation and damage in the central nervous system
• Lumbar puncture to analyze cerebrospinal fluid for signs of inflammation and immune system activity
• Visual evoked potentials to measure the electrical activity in the brain in response to visual stimuli

HLA-DRB1*1501 genotyping can also be a useful diagnostic tool for individuals who are experiencing symptoms of MS, particularly if they have a family history of the disease.

Conclusion

MS is a chronic autoimmune disorder that can cause a range of symptoms, including vision problems, muscle weakness, and difficulty with coordination and balance. HLA-DRB1*1501 genotyping is a test that can identify whether an individual carries the gene variant associated with an increased risk of developing MS. The cost of this test at DNA Labs India is INR 5250. Early diagnosis and treatment of MS can help to manage symptoms and improve quality of life.

For more information on HLA-DRB1*1501 genotyping and other genetic tests, contact DNA Labs India today.