Short Description

HLA-B*1502 Genotyping (Carbamazepine) is performed using Sanger Sequencing methodology. Sample that have to be given is Peripheral blood in EDTA Vacutainer (2ml) for this test. You can expect results in 7-10 days

PreTest Information

HLA-B*1502 Genotyping (Carbamazepine) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.

Detail Description

HLA-B*1502 Genotyping (Carbamazepine) cost INR:5250 symptoms diagnosis

HLA-B*1502 is a genetic variant that is associated with an increased risk of developing a severe skin reaction known as Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) when taking the medication carbamazepine. HLA-B*1502 genotyping is a test that can determine whether an individual carries this genetic variant, allowing doctors to make informed decisions about prescribing carbamazepine.

Symptoms of Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN)

SJS and TEN are both severe skin reactions that can be life-threatening. Symptoms typically start with flu-like symptoms such as fever, sore throat, and fatigue. This is followed by the appearance of a painful rash that spreads quickly and can cover the entire body. The skin may also blister and peel, leaving large areas of raw, exposed skin. SJS and TEN can also affect the mucous membranes, causing pain and swelling in the eyes, mouth, and genitals.

Diagnosis of HLA-B*1502 Genotyping

HLA-B*1502 genotyping is a simple blood test that can be ordered by a doctor or healthcare provider. The test looks for the presence of the HLA-B*1502 gene variant, which is associated with an increased risk of developing SJS or TEN when taking carbamazepine. The test is typically ordered for individuals who are about to start taking carbamazepine or who have previously experienced a severe skin reaction while taking the medication.

Cost of HLA-B*1502 Genotyping (Carbamazepine)

The cost of HLA-B*1502 genotyping can vary depending on the location and provider. In India, the cost of the test is typically around INR 5250. It is important to note that this cost may not include any additional fees or charges associated with the blood draw or consultation with a healthcare provider. It is important to check with the provider to determine the full cost of the test.

Conclusion

HLA-B*1502 genotyping is an important test for individuals who may be prescribed carbamazepine. The test can determine whether an individual carries the genetic variant associated with an increased risk of developing SJS or TEN when taking the medication. The cost of the test in India is typically around INR 5250, but it is important to check with the provider to determine the full cost. If you have been prescribed carbamazepine, talk to your doctor or healthcare provider about whether HLA-B*1502 genotyping is appropriate for you.

For more information about HLA-B*1502 genotyping and other DNA testing services, contact DNA Labs India.