Short Description

HLA A, B, C, DRB1, DQB1 (Any One) [Low Resolution] is performed using End Point PCR methodology. Sample that have to be given is Peripheral blood/ Buccal swabs (6-8 no.) in EDTA Vacutainer (2ml) for this test. You can expect results in 3-4 days

PreTest Information

HLA A, B, C, DRB1, DQB1 (Any One) [Low Resolution] can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.

Detail Description

HLA A, B, C, DRB1, DQB1 (Low Resolution) Test: Symptoms, Diagnosis and Cost

Human Leukocyte Antigen (HLA) testing is done to determine the compatibility of organ and tissue donors with recipients. It is also used to diagnose autoimmune diseases and genetic disorders. HLA typing is done by analyzing the genetic markers that are present on the surface of white blood cells. DNA Labs India offers a low-resolution HLA A, B, C, DRB1, DQB1 test that can help identify compatible donors and diagnose certain diseases.

Symptoms of Diseases Diagnosed by HLA Testing

HLA testing is used to diagnose several autoimmune diseases and genetic disorders. Some of the symptoms of these diseases are:

• Celiac Disease: Diarrhea, abdominal pain, weight loss, fatigue, and anemia
• Lupus: Fatigue, joint pain, rash, fever, and kidney problems
• Rheumatoid Arthritis: Joint pain, swelling, stiffness, and fatigue
• Ankylosing Spondylitis: Back pain, stiffness, and reduced mobility
• Sjogren's Syndrome: Dry eyes and mouth, joint pain, and fatigue

Diagnosis of Diseases using HLA Testing

HLA testing can be used to diagnose several autoimmune diseases and genetic disorders. Some of the diseases that can be diagnosed using HLA testing are:

• Celiac Disease: HLA-DQ2 or HLA-DQ8 antigens are present in 95% of people with celiac disease
• Lupus: HLA-DR2 and HLA-DR3 antigens are present in people with lupus
• Rheumatoid Arthritis: HLA-DR4 antigen is present in people with rheumatoid arthritis
• Ankylosing Spondylitis: HLA-B27 antigen is present in people with ankylosing spondylitis
• Sjogren's Syndrome: HLA-DR3 and HLA-DR5 antigens are present in people with Sjogren's syndrome

HLA A, B, C, DRB1, DQB1 (Low Resolution) Test Cost

The cost of the HLA A, B, C, DRB1, DQB1 (Low Resolution) test at DNA Labs India is INR 5250. The test is performed using PCR-SSP (Polymerase Chain Reaction-Sequence Specific Primers) method.

Conclusion

HLA testing is an important tool in diagnosing autoimmune diseases and genetic disorders. It is also used to determine the compatibility of organ and tissue donors with recipients. The low-resolution HLA A, B, C, DRB1, DQB1 test offered by DNA Labs India can help identify compatible donors and diagnose certain diseases. The test is performed using PCR-SSP method and costs INR 5250.