Short Description

Preparation of Hi-C library, 2x150 PE Hiseq sequencing to generate 200 million reads (R1+R2). Genome digestion for restriction enzymes, HiCUP analysis, Bam files without artifacts and duplicates. Deliverables does not include data visualisation, loci interaction analysis.

PreTest Information

Detail Description

Hi-C Sequencing and Analysis Cost in India: All You Need to Know

DNA Labs India is a leading provider of Hi-C sequencing and analysis services in India. Hi-C sequencing is a powerful technique that allows the investigation of three-dimensional chromatin structure and genome organization. It involves the fixation, digestion, and ligation of chromatin, followed by high-throughput sequencing of the resulting DNA fragments.

At DNA Labs India, we offer Hi-C sequencing and analysis services at a cost of INR 185,000. This includes sample preparation, sequencing, and data analysis.

What is Hi-C Sequencing?

Hi-C sequencing is a technique that enables the study of the three-dimensional structure of chromatin in the nucleus of a cell. It involves the cross-linking of chromatin, followed by digestion and ligation of the resulting DNA fragments. The ligated fragments are then sequenced to generate a library of DNA sequences that can be used to reconstruct the spatial organization of the genome.

The Hi-C technique has revolutionized our understanding of genome organization and has been used to investigate a wide range of biological processes, including gene regulation, chromatin folding, and genome evolution.

What are the Benefits of Hi-C Sequencing?

Hi-C sequencing has several benefits over other techniques for studying chromatin structure and genome organization. These include:

• Ability to study the three-dimensional structure of chromatin
• High resolution mapping of chromatin interactions
• Identification of long-range chromatin interactions
• Discovery of novel chromatin domains

What is the Cost of Hi-C Sequencing and Analysis at DNA Labs India?

At DNA Labs India, we offer Hi-C sequencing and analysis services at a cost of INR 185,000. This includes:

• Sample preparation
• Hi-C sequencing using Illumina platforms
• Data analysis using state-of-the-art bioinformatics tools

Our team of experts will work closely with you to ensure that you receive the highest quality results and the best possible value for your investment.

How is Hi-C Sequencing Used in Diagnosis?

Hi-C sequencing has several potential applications in diagnosis, including:

• Identification of disease-associated chromatin interactions
• Discovery of novel disease-associated chromatin domains
• Identification of disease-associated gene regulatory networks

By studying the three-dimensional structure of chromatin in diseased tissues, Hi-C sequencing has the potential to identify novel disease mechanisms and drug targets. It can also be used to develop personalized therapies based on an individual's unique chromatin structure.

Conclusion

Hi-C sequencing is a powerful technique that enables the investigation of three-dimensional chromatin structure and genome organization. At DNA Labs India, we offer Hi-C sequencing and analysis services at a cost of INR 185,000. Our team of experts will work closely with you to ensure that you receive the highest quality results and the best possible value for your investment.

If you are interested in learning more about our Hi-C sequencing and analysis services, please contact us today.