Short Description

In females the ratio of Factor VIII activity to the level of vWF antigen is used to predict carrier status. Ratios less than 1 identify 95-99% of Hemophilia A carriers.

PreTest Information

Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory. It is recommended that patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent of treating Physician.

Detail Description

HEMOPHILIA A CARRIER DETECTION Test: Symptoms, Diagnosis, and Cost

Hemophilia A is a genetic disorder that affects the blood's ability to clot. It is caused by a deficiency in clotting factor VIII, which leads to excessive bleeding and bruising. Hemophilia A is an X-linked recessive disorder, which means that the condition is carried on the X chromosome.

Women can be carriers of Hemophilia A, which means they have one normal X chromosome and one with the Hemophilia A gene. Carriers do not typically experience symptoms of Hemophilia A, but they can pass the gene on to their children.

Hemophilia A carrier detection test is a genetic test that can determine if a woman is a carrier of Hemophilia A. The test can also be used to determine if a man is a carrier, but this is rare as they typically have symptoms if they possess the Hemophilia A gene.

Symptoms of Hemophilia A

Hemophilia A is a bleeding disorder, and the primary symptoms are related to excessive bleeding and bruising. The severity of the symptoms can vary depending on the level of clotting factor VIII in the blood.

Common symptoms of Hemophilia A include:

• Excessive bleeding after injury or surgery
• Frequent nosebleeds
• Bruising easily
• Blood in the urine or stool
• Prolonged bleeding after dental work
• Joint pain and swelling
• Headaches

Diagnosis of Hemophilia A

Hemophilia A is typically diagnosed through a blood test that measures the clotting factor VIII level. If the level is low, a diagnosis of Hemophilia A is likely.

In addition to the blood test, doctors may also perform a physical exam and take a medical history to determine if a person has other risk factors for Hemophilia A.

Hemophilia A Carrier Detection Test Cost

The Hemophilia A carrier detection test is a genetic test that can be performed at specialized labs. The cost of the test can vary depending on the lab and the location, but it typically ranges from INR 14,500 to INR 20,000.

It is important to note that the cost of the test may not be covered by insurance, so it is important to check with your insurance provider to see if the test is covered.

Conclusion

Hemophilia A carrier detection test is an important tool for identifying carriers of the Hemophilia A gene. If you have a family history of Hemophilia A or are concerned that you may be a carrier, talk to your doctor about the Hemophilia A carrier detection test. The cost of the test can vary, so it is important to do your research and check with your insurance provider to see if the test is covered.

In females the ratio of Factor VIII activity to the level of vWF antigen is used to predict carrier status. Ratios less than 1 identify 95-99% of Hemophilia A carriers.