Short Description

NGS genetic DNA test detecets for variant and mutation detection in HBG2 gene for Hereditary persistence of fetal hemoglobin

PreTest Information

Clinical History of Patient who is going for HBG2 Gene Hereditary persistence of fetal hemoglobin NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with HBG2 Gene Hereditary persistence of fetal hemoglobin NGS Genetic DNA Test gene HBG2

Detail Description

HBG2 Gene Hereditary Persistence of Fetal Hemoglobin NGS Genetic DNA Test

Hereditary persistence of fetal hemoglobin (HPFH) is a genetic condition characterized by the continued production of fetal hemoglobin (HbF) into adulthood. This condition is caused by mutations in the HBG2 gene, which encodes the beta-globin subunit of HbF. The HBG2 gene is located on chromosome 11 and is involved in the regulation of HbF production.

HPFH is a rare condition that affects approximately 1 in 2,500 individuals worldwide. It is most commonly found in individuals of African, Mediterranean, and Middle Eastern descent. Individuals with HPFH have higher levels of HbF in their blood, which can provide some protection against certain blood disorders, such as sickle cell anemia and beta-thalassemia.

Symptoms of HPFH

Most individuals with HPFH do not experience any symptoms. However, some individuals may have mild anemia or jaundice.

Diagnosis of HPFH

HPFH can be diagnosed through genetic testing. Next-generation sequencing (NGS) is a powerful tool that can be used to identify mutations in the HBG2 gene. NGS is a high-throughput DNA sequencing technology that can analyze millions of DNA sequences simultaneously, making it an efficient and cost-effective method for genetic testing.

NGS Genetic DNA Test Cost

The cost of NGS genetic DNA testing for HPFH in India is approximately INR 20,000. This cost may vary depending on the specific testing laboratory and the extent of the genetic analysis required.

Conclusion

HPFH is a rare genetic condition that can be diagnosed through NGS genetic DNA testing. This testing can provide valuable information about an individual's risk for certain blood disorders and may be helpful in guiding treatment decisions. The cost of NGS genetic DNA testing for HPFH in India is approximately INR 20,000.

At DNA Labs India, we offer a wide range of genetic testing services, including NGS genetic DNA testing for HPFH. Our team of experienced geneticists and laboratory technicians use state-of-the-art technology to provide accurate and reliable test results. Contact us today to learn more about our testing services.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for HBG2 Gene Hereditary persistence of fetal hemoglobin NGS Genetic DNA Test