Short Description

NGS genetic DNA test detecets for variant and mutation detection in HBB gene for Sickle cell anemia

PreTest Information

Clinical History of Patient who is going for HBB Gene Sickle cell anemia NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with HBB Gene Sickle cell anemia NGS Genetic DNA Test gene HBB

Detail Description

HBB Gene and Sickle Cell Anemia: NGS Genetic DNA Test Cost and Diagnosis

Sickle cell anemia is a genetic disorder that affects the red blood cells. It is caused by a mutation in the HBB gene, which provides instructions to make a protein called hemoglobin. Hemoglobin is responsible for carrying oxygen throughout the body. In individuals with sickle cell anemia, the mutated HBB gene leads to the production of abnormal hemoglobin. These abnormal hemoglobin molecules tend to stick together and form a rigid, sickle shape. This causes the red blood cells to become stiff and crescent-shaped, which makes it difficult for them to pass through blood vessels.

Sickle cell anemia is a hereditary condition, which means it is passed down from parents to their children. If both parents have the sickle cell trait, there is a 25% chance that their child will inherit the disease. The symptoms of sickle cell anemia can vary widely and can include:

• Painful episodes called sickle cell crises
• Anemia (low red blood cell count)
• Fatigue
• Jaundice
• Swelling of the hands and feet
• Delayed growth and puberty
• Vision problems
• Stroke

Diagnosis of sickle cell anemia involves a physical exam, blood tests, and genetic testing. Genetic testing is used to confirm the presence of the HBB gene mutation that causes sickle cell anemia. Next-generation sequencing (NGS) genetic testing is a powerful tool that can be used to detect a wide range of genetic mutations, including those that cause sickle cell anemia. NGS genetic testing is fast, accurate, and can detect mutations that other types of genetic tests may miss.

The cost of NGS genetic testing for sickle cell anemia can vary depending on the lab and the specific tests ordered. At DNA Labs India, we offer NGS genetic testing for sickle cell anemia at a cost of INR 20,000. This test uses the latest NGS technology to detect mutations in the HBB gene that cause sickle cell anemia. Our test is fast, accurate, and reliable, and can provide valuable information for individuals and families affected by sickle cell anemia.

In conclusion, sickle cell anemia is a genetic disorder that can have serious health consequences. The HBB gene mutation that causes sickle cell anemia can be detected through genetic testing, including NGS genetic testing. At DNA Labs India, we offer fast, accurate, and affordable NGS genetic testing for sickle cell anemia. If you or a loved one is affected by sickle cell anemia, contact us today to learn more about our testing services.