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Accurate Test Results for GRHL3 Gene van der Woude syndrome type 2 NGS Genetic DNA Test
GRHL3 Gene van der Woude syndrome type 2 NGS Genetic DNA Test Cost 20000 Rs
GRHL3 Gene van der Woude syndrome type 2 NGS Genetic DNA Test Details
GRHL3 Gene and Van der Woude Syndrome Type 2: NGS Genetic DNA Test Cost INR 20,000, Symptoms, and Diagnosis
Van der Woude Syndrome (VWS) is a rare genetic disorder characterized by the presence of oral clefts and lip pits. VWS is caused by mutations in the IRF6 gene, which is responsible for the development of the oral cavity and the lip. However, there is a subtype of VWS known as Van der Woude Syndrome Type 2 (VWS2), which is caused by mutations in the GRHL3 gene.
GRHL3 Gene and VWS2
The GRHL3 gene is responsible for the development of the oral epithelium, which is the tissue that lines the oral cavity. Mutations in the GRHL3 gene have been found to cause VWS2, which is characterized by the presence of oral clefts, lip pits, and other craniofacial abnormalities.
VWS2 is inherited in an autosomal dominant pattern, which means that a person with a mutation in the GRHL3 gene has a 50% chance of passing the mutation on to their children.
Symptoms of VWS2
The symptoms of VWS2 are similar to those of VWS, but with some notable differences. The most common symptoms of VWS2 include:
- Oral clefts
- Lip pits
- Craniofacial abnormalities, such as a cleft palate or a small jaw
- Abnormalities in the teeth and gums
It is important to note that not all individuals with VWS2 will have all of these symptoms. The severity of the symptoms can vary widely between individuals.
Diagnosis of VWS2
VWS2 can be diagnosed through genetic testing. Next-Generation Sequencing (NGS) is a powerful tool that can detect mutations in the GRHL3 gene. NGS is a type of genetic testing that can sequence large amounts of DNA quickly and accurately.
NGS genetic DNA testing for VWS2 is offered by DNA Labs India. The cost of the test is INR 20,000. The test is performed on a blood or saliva sample, and the results are typically available within 2-3 weeks.
Conclusion
Van der Woude Syndrome Type 2 is a rare genetic disorder caused by mutations in the GRHL3 gene. The symptoms of VWS2 include oral clefts, lip pits, and craniofacial abnormalities. Genetic testing using NGS technology can diagnose VWS2, and DNA Labs India offers this test at a cost of INR 20,000. If you suspect that you or a loved one may have VWS2, it is important to seek medical advice and consider genetic testing.
At DNA Labs India, we are committed to providing accurate and reliable genetic testing services. Contact us today to learn more about our testing options.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for GRHL3 Gene van der Woude syndrome type 2 NGS Genetic DNA Test
