Short Description

NGS genetic DNA test detecets for variant and mutation detection in GPD1L gene for Brugada syndrome type 2

PreTest Information

Clinical History of Patient who is going for GPD1L Gene Brugada syndrome type 2 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with GPD1L Gene Brugada syndrome type 2 NGS Genetic DNA Test gene GPD1L

Detail Description

GPD1L Gene and Brugada Syndrome Type 2: Understanding the Role of NGS Genetic DNA Test

Brugada Syndrome Type 2 is a rare genetic disorder that affects the electrical activity of the heart. It is caused by mutations in the GPD1L gene, which codes for an enzyme involved in the metabolism of glucose. This disorder can lead to life-threatening arrhythmias and sudden cardiac death. However, early diagnosis and treatment can significantly improve the prognosis.

Symptoms of Brugada Syndrome Type 2

Brugada Syndrome Type 2 is often asymptomatic until a cardiac event occurs. However, some individuals may experience symptoms such as:

• Fainting or syncope
• Palpitations or irregular heartbeat
• Dizziness or lightheadedness
• Shortness of breath

These symptoms can be triggered by various factors such as fever, alcohol consumption, or certain medications.

Diagnosis of Brugada Syndrome Type 2

The diagnosis of Brugada Syndrome Type 2 typically involves a combination of clinical evaluation, electrocardiogram (ECG), and genetic testing. The ECG can detect characteristic abnormalities in the heart rhythm that are indicative of the disorder. However, genetic testing is necessary to confirm the diagnosis and identify the specific mutation in the GPD1L gene.

NGS Genetic DNA Test for Brugada Syndrome Type 2

Next-generation sequencing (NGS) is a powerful genetic testing technology that can analyze multiple genes simultaneously. This allows for a more comprehensive and efficient evaluation of genetic disorders such as Brugada Syndrome Type 2. The NGS test for Brugada Syndrome Type 2 involves sequencing the GPD1L gene and other genes associated with the disorder. The test can detect both known and novel mutations in the genes.

Cost of NGS Genetic DNA Test for Brugada Syndrome Type 2 in India

The cost of the NGS Genetic DNA Test for Brugada Syndrome Type 2 in India is approximately INR 20,000. The cost may vary depending on the specific laboratory and location.

Conclusion

Early diagnosis and treatment are crucial for individuals with Brugada Syndrome Type 2. The NGS Genetic DNA Test can provide a more comprehensive and efficient evaluation of the disorder, leading to better diagnosis and treatment options. If you or a family member has symptoms or a family history of the disorder, it is recommended to consult a healthcare provider and consider genetic testing.

At DNA Labs India, we offer reliable and accurate NGS Genetic DNA testing services for Brugada Syndrome Type 2 and other genetic disorders. Contact us today to learn more.