Short Description

Glioma Panel(MGMT, IDH1&2, FISH 1p19q) is performed using MLPA + FISH + Sanger Sequencing methodology. Sample that have to be given is Tumor tissue in Paraffin embedded tissue blocks for this test. You can expect results in 2-3 weeks

PreTest Information

Glioma Panel(MGMT, IDH1&2, FISH 1p19q) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.

Detail Description

Glioma Panel(MGMT, IDH1&2, FISH 1p19q) cost INR:36000 symptoms diagnosis

Gliomas are the most common type of primary brain tumors, which originate in the brain and spinal cord. These tumors can be cancerous or non-cancerous and can affect people of all ages. The treatment and prognosis of gliomas depend on the type and grade of the tumor, which can only be determined through a proper diagnosis.

DNA Labs India offers a comprehensive glioma panel that includes MGMT, IDH1&2, and FISH 1p19q tests. These tests can help in the diagnosis and treatment of gliomas and provide important information about the tumor's genetic makeup.

MGMT Test

The MGMT test is used to determine the methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) gene. This gene is responsible for repairing DNA damage caused by chemotherapy and radiation therapy. If the MGMT gene is methylated, it indicates that the tumor is more responsive to chemotherapy and radiation therapy.

IDH1&2 Test

The IDH1&2 test is used to determine the mutation status of the isocitrate dehydrogenase (IDH) 1 and 2 genes. These genes play a crucial role in cellular metabolism and energy production. The IDH1&2 mutation is found in most low-grade gliomas and secondary glioblastomas and is associated with a better prognosis.

FISH 1p19q Test

The FISH 1p19q test is used to determine the loss of heterozygosity (LOH) of chromosomes 1p and 19q. The LOH of these chromosomes is found in most oligodendrogliomas, which are a type of glioma. The FISH 1p19q test can help in the diagnosis and treatment of oligodendrogliomas.

Cost of Glioma Panel

The cost of the glioma panel, which includes MGMT, IDH1&2, and FISH 1p19q tests, is INR 36000. This cost includes all the necessary laboratory tests and reports.

Symptoms of Gliomas

The symptoms of gliomas vary depending on the location and size of the tumor. Some of the common symptoms include:

• Headaches
• Nausea and vomiting
• Seizures
• Memory loss
• Speech difficulties
• Weakness or numbness in the limbs

If you experience any of these symptoms, it is important to consult a doctor immediately.

Diagnosis of Gliomas

The diagnosis of gliomas involves a series of tests, including imaging tests such as MRI, CT, and PET scans. A biopsy may also be performed to confirm the diagnosis and determine the type and grade of the tumor.

The glioma panel offered by DNA Labs India can provide important information about the genetic makeup of the tumor, which can help in the diagnosis and treatment of gliomas.

Conclusion

The glioma panel offered by DNA Labs India is a comprehensive test that can provide important information about the genetic makeup of gliomas. The tests included in the panel can help in the diagnosis and treatment of gliomas and provide important information about the prognosis of the tumor. If you experience any symptoms of gliomas, it is important to consult a doctor immediately and get the necessary tests done.

For more information about the glioma panel and other genetic testing services offered by DNA Labs India, please visit their website.