Short Description

NGS genetic DNA test detecets for variant and mutation detection in GLA gene for Fabry disease

PreTest Information

Clinical History of Patient who is going for GLA Gene Fabry disease NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Fabry disease

Detail Description

Understanding GLA Gene Fabry Disease: NGS Genetic DNA Test Cost and Symptoms Diagnosis in India

GLA Gene Fabry disease is a rare genetic disorder that affects the body's ability to metabolize a specific type of fat. The disease is caused by a mutation in the GLA gene, which provides instructions for producing an enzyme called alpha-galactosidase A. Without this enzyme, the body cannot break down a type of fat called globotriaosylceramide (Gb3), which can accumulate in the body's cells and tissues, leading to a range of symptoms and health problems.

Symptoms of GLA Gene Fabry Disease

The symptoms of GLA Gene Fabry disease can vary widely depending on the severity of the condition and the age at which it first appears. Some of the most common symptoms include:

• Episodes of pain or burning sensations in the hands and feet
• Clusters of small, dark red spots on the skin (angiokeratomas)
• Hearing loss
• Clouding of the cornea
• Gastrointestinal problems, such as diarrhea and abdominal pain
• Heart problems, including arrhythmia and heart attack

Diagnosis of GLA Gene Fabry Disease

Diagnosing GLA Gene Fabry disease can be challenging, as the symptoms can be similar to those of other conditions. However, there are several tests that can help identify the condition, including:

• Blood tests to measure the levels of alpha-galactosidase A and Gb3
• Genetic testing to look for mutations in the GLA gene
• Biopsies of the skin, kidney, or heart to look for the accumulation of Gb3

NGS Genetic DNA Test Cost for GLA Gene Fabry Disease in India

NGS genetic DNA testing is a powerful tool for diagnosing genetic disorders like GLA Gene Fabry disease. This type of testing uses next-generation sequencing technology to analyze a person's DNA and identify mutations in specific genes.

The cost of NGS genetic DNA testing for GLA Gene Fabry disease in India can vary depending on the provider and the specific tests that are needed. However, on average, the cost of NGS genetic DNA testing for GLA Gene Fabry disease in India is around INR 20,000.

Conclusion

GLA Gene Fabry disease is a rare genetic disorder that can cause a range of symptoms and health problems. If you or a loved one is experiencing symptoms of GLA Gene Fabry disease, it's important to seek medical attention and undergo testing to determine the underlying cause. NGS genetic DNA testing is a powerful tool for diagnosing genetic disorders like GLA Gene Fabry disease, and the cost of testing in India is generally affordable. By getting tested and receiving appropriate treatment, individuals with GLA Gene Fabry disease can manage their symptoms and improve their quality of life.

For more information on GLA Gene Fabry disease and NGS genetic DNA testing, contact DNA Labs India today.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for GLA Gene Fabry disease NGS Genetic DNA Test