Short Description

NGS genetic DNA test detecets for variant and mutation detection in GJB3 gene for Deafness, autosomal recessive

PreTest Information

Clinical History of Patient who is going for SLC52A3 Gene Brown-Vialetto-Van Laere syndrome 1 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with SLC52A3 Gene Brown-Vialetto-Van Laere syndrome 1 NGS Genetic DNA Test gene SLC52A8

Detail Description

GJB3 Gene Deafness: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost in India

Deafness is a common genetic disorder that affects people across the globe. One of the most common forms of deafness is caused by mutations in the GJB3 gene, which is responsible for producing a protein that helps in the formation of the inner ear. The GJB3 gene deafness is an autosomal recessive disorder, which means that the condition can only be inherited if both parents carry the mutated gene.

Symptoms of GJB3 Gene Deafness

The symptoms of GJB3 gene deafness can vary from mild to severe and may include:

• Difficulty in hearing and understanding speech
• Delayed speech development in children
• Tinnitus or ringing in the ears
• Inability to hear high-pitched sounds
• Sensitivity to loud noises
• Difficulty in hearing in noisy environments

The severity of the symptoms depends on the extent of the hearing loss and the age at which the hearing loss occurs.

Diagnosis of GJB3 Gene Deafness

The diagnosis of GJB3 gene deafness is usually made through a combination of hearing tests and genetic testing. The hearing tests may include:

• Pure-tone audiometry
• Tympanometry
• Otoacoustic emissions
• Auditory brainstem response

Genetic testing involves analyzing the DNA of the affected person to look for mutations in the GJB3 gene. The genetic test can be performed using a variety of techniques, including:

• PCR-based sequencing
• Next-generation sequencing (NGS)
• Sanger sequencing

NGS Genetic DNA Test Cost for GJB3 Gene Deafness in India

The cost of NGS genetic DNA testing for GJB3 gene deafness in India can vary depending on the laboratory and the type of test being performed. On average, the cost of NGS genetic DNA testing for GJB3 gene deafness in India can range from INR 15,000 to INR 25,000. However, it is important to note that the cost of the test may vary based on the specific laboratory and the individual's insurance coverage.

Conclusion

GJB3 gene deafness is a common genetic disorder that can cause hearing loss in individuals. The symptoms of GJB3 gene deafness can vary from mild to severe, and the condition can be diagnosed through a combination of hearing tests and genetic testing. NGS genetic DNA testing for GJB3 gene deafness is available in India and can help individuals determine whether they carry the mutated gene. The cost of the test may vary depending on the laboratory and insurance coverage, but it is important to consider the benefits of early detection and treatment of this condition.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for GJB3 Gene Deafness, autosomal recessive NGS Genetic DNA Test