Short Description

NGS genetic DNA test detecets for variant and mutation detection in GDF1 gene for Transposition of great arteries, dextro-looped 3

PreTest Information

Clinical History of Patient who is going for GDF1 Gene Transposition of great arteries, dextro-looped 3 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with GDF1 Gene Transposition of great arteries, dextro-looped 3 NGS Genetic DNA Test gene GDF1

Detail Description

GDF1 Gene Transposition of Great Arteries – Symptoms, Diagnosis and NGS Genetic DNA Test Cost in India

Transposition of Great Arteries (TGA) is a congenital heart defect where the two main arteries that carry blood away from the heart, the aorta and the pulmonary artery, are switched in position. This means that oxygen-poor blood is circulated to the body instead of the lungs, and oxygen-rich blood is circulated to the lungs instead of the body. The GDF1 gene has been found to play a crucial role in the development of the heart and its associated structures. Mutations in this gene have been linked to TGA, specifically dextro-looped 3 TGA, which accounts for about 5% of all TGA cases.

Symptoms of GDF1 Gene Transposition of Great Arteries

The symptoms of TGA can vary depending on the severity of the defect. Some babies may show no signs of the condition at birth, while others may develop serious complications soon after birth. Some common symptoms of TGA include:

• Blue tint to the skin, lips, and nails (cyanosis)
• Rapid breathing
• Poor feeding or difficulty breathing while feeding
• Fatigue and weakness

Diagnosis of GDF1 Gene Transposition of Great Arteries

Doctors may suspect TGA based on the symptoms a baby displays shortly after birth. A physical exam may reveal a heart murmur or abnormal heart sounds. To confirm the diagnosis, doctors may order a series of tests, including:

• Echocardiogram
• Electrocardiogram (ECG)
• Chest X-ray
• Magnetic resonance imaging (MRI)

NGS Genetic DNA Test for GDF1 Gene Transposition of Great Arteries

Next-generation sequencing (NGS) is a powerful tool for identifying genetic mutations that may be responsible for TGA. The GDF1 gene is one of many genes that can be analyzed using NGS. This test involves sequencing the entire gene to identify any mutations that may be present. The cost of an NGS genetic DNA test for GDF1 Gene Transposition of Great Arteries in India is around INR 20,000. This test can be done on a blood sample or a cheek swab.

Conclusion

GDF1 Gene Transposition of Great Arteries is a serious congenital heart defect that can cause significant health problems if left untreated. Early diagnosis and treatment are essential for improving outcomes. NGS genetic DNA testing can help identify the underlying genetic mutations that may be responsible for TGA, allowing doctors to develop an effective treatment plan. If you suspect that your baby may have TGA, it is important to seek medical attention right away.

At DNA Labs India, we offer a range of genetic testing services, including NGS genetic DNA testing for GDF1 Gene Transposition of Great Arteries. Our team of experienced geneticists and technicians uses the latest technology and equipment to provide accurate and reliable results. Contact us today to learn more about our services.