Short Description

NGS genetic DNA test detecets for variant and mutation detection in GCK gene for Hyperinsulinemic hypoglycemia type 3

PreTest Information

Clinical History of Patient who is going for GCK Gene Hyperinsulinemic hypoglycemia type 3 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Hyperinsulinemic hypoglycemia type 3

Detail Description

GCK Gene Hyperinsulinemic Hypoglycemia Type 3 NGS Genetic DNA Test Cost INR:20000 Symptoms Diagnosis

Hyperinsulinemic hypoglycemia type 3 (HH3) is a rare genetic disorder that causes low blood sugar levels due to excessive insulin secretion. The condition is caused by mutations in the GCK gene, which encodes the enzyme glucokinase. Glucokinase is responsible for regulating insulin secretion in response to changes in blood glucose levels. In HH3, mutations in the GCK gene result in abnormally high levels of insulin secretion, leading to hypoglycemia.

Symptoms of HH3

The symptoms of HH3 can vary from person to person and may include:

• Low blood sugar levels (hypoglycemia)
• Headaches
• Dizziness
• Confusion
• Seizures
• Coma

The severity of symptoms can vary depending on the degree of hypoglycemia.

Diagnosis of HH3

Diagnosis of HH3 involves a combination of clinical evaluation, laboratory tests, and genetic testing. Laboratory tests can include measurement of blood glucose levels, insulin levels, and other hormones involved in glucose regulation. Genetic testing of the GCK gene can confirm the diagnosis.

NGS Genetic DNA Test for HH3

Next-generation sequencing (NGS) genetic DNA testing can identify mutations in the GCK gene that cause HH3. NGS testing is a high-throughput method that can sequence large amounts of DNA quickly and accurately. This type of testing can identify mutations that may be missed by other genetic testing methods.

Cost of NGS Genetic DNA Test for HH3

The cost of NGS genetic DNA testing for HH3 can vary depending on the laboratory and location. In India, the cost of the test is typically around INR 20,000.

Conclusion

HH3 is a rare genetic disorder that can cause low blood sugar levels due to excessive insulin secretion. Diagnosis involves clinical evaluation, laboratory tests, and genetic testing. NGS genetic DNA testing can identify mutations in the GCK gene that cause HH3. The cost of the test in India is typically around INR 20,000.

At DNA Labs India, we offer NGS genetic DNA testing for HH3 and other genetic disorders. Our testing is accurate, reliable, and affordable. Contact us today to learn more.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for GCK Gene Hyperinsulinemic hypoglycemia type 3 NGS Genetic DNA Test