Short Description

NGS genetic DNA test detecets for variant and mutation detection in GBA gene for Parkinson disease, late-onset, susceptibility to

PreTest Information

Clinical History of Patient who is going for GBA Gene Parkinson disease, late-onset, susceptibility to NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with GBA Gene Parkinson disease, late-onset, susceptibility to

Detail Description

GBA Gene Parkinson Disease: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost in India

Parkinson's Disease is a neurodegenerative disorder that affects the central nervous system, causing tremors, stiffness, and difficulty with movement. It is a progressive disease that affects over 10 million people worldwide, and there is no cure for it yet. However, scientists are making strides in understanding the genetic basis of Parkinson's Disease, which may help with early diagnosis and treatment.

One of the genes that have been linked to Parkinson's Disease is the GBA gene. Mutations in the GBA gene have been found to increase the risk of developing Parkinson's Disease, particularly the late-onset form of the disease. The GBA gene provides instructions for making an enzyme called glucocerebrosidase, which helps break down a fatty substance called glucosylceramide. Mutations in the GBA gene result in a deficiency of this enzyme, leading to the accumulation of glucosylceramide in certain cells, including neurons in the brain, which may contribute to the development of Parkinson's Disease.

Symptoms of Parkinson's Disease

The symptoms of Parkinson's Disease can vary from person to person, but they typically include:

• Tremors or shaking in the hands, arms, legs, or jaw
• Stiffness or rigidity in the limbs and trunk
• Slowness of movement or bradykinesia
• Poor balance and coordination
• Difficulty with speech and swallowing

These symptoms can worsen over time, and they can have a significant impact on a person's quality of life.

Diagnosis of Parkinson's Disease

Diagnosing Parkinson's Disease can be challenging, as there are no specific tests for it. Instead, doctors rely on a combination of clinical observation and medical history. They may also use imaging tests, such as MRI or CT scans, to rule out other conditions that can cause similar symptoms.

One promising approach to diagnosing Parkinson's Disease is through genetic testing. By analyzing a person's DNA, doctors can look for mutations in genes that are associated with the disease, such as the GBA gene. This can help with early diagnosis and treatment, which may slow the progression of the disease.

NGS Genetic DNA Test Cost in India

The cost of NGS Genetic DNA testing in India can vary depending on the laboratory and the specific test being performed. However, on average, the cost of NGS Genetic DNA testing for Parkinson's Disease susceptibility is around INR 20,000. This may seem expensive, but early diagnosis and treatment can help reduce the overall cost of managing the disease.

Conclusion

Parkinson's Disease is a debilitating condition that affects millions of people worldwide. Understanding the genetic basis of the disease, such as mutations in the GBA gene, can help with early diagnosis and treatment. NGS Genetic DNA testing can be a valuable tool in diagnosing Parkinson's Disease, and while it may be costly, the benefits of early diagnosis and treatment can far outweigh the cost in the long run.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for GBA Gene Parkinson disease, late-onset, susceptibility to NGS Genetic DNA Test