Short Description

NGS genetic DNA test detecets for variant and mutation detection in GBA gene for Lewy body dementia, susceptibility to

PreTest Information

Clinical History of Patient who is going for GBA Gene Lewy body dementia, susceptibility to NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with GBA Gene Lewy body dementia, susceptibility to

Detail Description

GBA Gene and Lewy Body Dementia: Susceptibility and NGS Genetic DNA Test

Lewy Body Dementia (LBD) is a type of dementia that affects around 1.4 million people in the United States alone. It is a progressive condition that involves the accumulation of abnormal protein deposits in the brain, called Lewy bodies. These deposits cause a range of symptoms, including cognitive decline, hallucinations, and motor problems.

Recent research has shown that a specific gene, called GBA, may increase a person's susceptibility to developing LBD. This gene produces an enzyme that is involved in the breakdown of certain types of fats in the brain. Mutations in the GBA gene can lead to a build-up of these fats, which in turn can contribute to the formation of Lewy bodies.

NGS Genetic DNA Test

The good news is that it is now possible to test for the presence of GBA gene mutations using Next-Generation Sequencing (NGS) technology. This type of genetic test involves sequencing the entire GBA gene to identify any mutations that may be present. The test is highly accurate and can provide valuable information about a person's risk of developing LBD.

Cost of NGS Genetic DNA Test

The cost of an NGS Genetic DNA Test for the GBA gene is around INR 20,000. While this may seem like a significant investment, it is important to remember that the test can provide valuable information about a person's health that could potentially save them from developing a debilitating condition like LBD.

Symptoms and Diagnosis of Lewy Body Dementia

The symptoms of LBD can be similar to those of other types of dementia, such as Alzheimer's disease. However, there are some key differences that can help doctors make a diagnosis. Some of the most common symptoms of LBD include:

• Visual hallucinations
• Cognitive problems, including memory loss and confusion
• Movement problems, including tremors and stiffness
• Sleep disturbances
• Mood and behavior changes

If you or a loved one is experiencing any of these symptoms, it is important to seek medical attention. A doctor can perform a variety of tests to help diagnose LBD, including a physical exam, neurological evaluation, and brain imaging studies.

Conclusion

The GBA gene has been linked to an increased risk of developing Lewy Body Dementia. Fortunately, it is now possible to test for the presence of GBA gene mutations using NGS Genetic DNA testing. While the cost of the test may be significant, the information it provides can be invaluable in helping people manage their health and potentially avoid developing a debilitating condition like LBD. If you or a loved one is experiencing symptoms of dementia, it is important to seek medical attention to determine the underlying cause and explore available treatment options.

If you are interested in learning more about genetic testing for LBD susceptibility, DNA Labs India offers a range of NGS Genetic DNA tests that can help you better understand your health risks. Contact us today to learn more.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for GBA Gene Lewy body dementia, susceptibility to NGS Genetic DNA Test