Short Description

NGS genetic DNA test detecets for variant and mutation detection in G6PD gene for Hemolytic anemia due to G6PD deficiency

PreTest Information

Clinical History of Patient who is going for G6PD Gene Hemolytic anemia due to G6PD deficiency NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Hemolytic anemia due to G6PD deficiency

Detail Description

G6PD Gene Hemolytic Anemia Due to G6PD Deficiency NGS Genetic DNA Test

G6PD deficiency is a genetic disorder that affects the function of red blood cells. The G6PD gene provides instructions for making an enzyme called glucose-6-phosphate dehydrogenase, which helps to protect red blood cells from damage. When someone has a G6PD deficiency, their red blood cells are more susceptible to damage from certain medications, infections, and other factors. This can lead to a type of anemia called hemolytic anemia, in which red blood cells are destroyed faster than they can be replaced.

Symptoms of G6PD Deficiency Hemolytic Anemia

People with G6PD deficiency may not show any symptoms until they are exposed to a trigger that causes hemolysis (destruction of red blood cells). Some common triggers include:

• Infections, particularly those caused by certain bacteria or viruses
• Certain medications, such as antibiotics, antimalarials, and aspirin
• Fava beans or other foods containing certain chemicals
• Exposure to chemicals or toxins, such as naphthalene (found in mothballs) or benzene

When hemolysis occurs, it can cause symptoms such as:

• Jaundice (yellowing of the skin and eyes)
• Pale skin
• Fatigue or weakness
• Shortness of breath
• Rapid heart rate
• Dark urine

Diagnosis of G6PD Deficiency Hemolytic Anemia

G6PD deficiency is usually diagnosed through a blood test that measures the activity of the G6PD enzyme. However, because G6PD activity can vary over time and may be affected by recent exposure to triggers, it is important to time the test carefully. In some cases, genetic testing may be used to confirm a diagnosis of G6PD deficiency.

NGS Genetic DNA Test for G6PD Deficiency Hemolytic Anemia

Next-generation sequencing (NGS) is a type of genetic testing that can be used to identify mutations in the G6PD gene that cause G6PD deficiency. This test can provide more detailed information about a person's genetic makeup than traditional blood tests, and may be particularly useful in cases where G6PD activity levels are borderline or difficult to interpret.

Cost of NGS Genetic DNA Test for G6PD Deficiency Hemolytic Anemia

The cost of an NGS genetic DNA test for G6PD deficiency hemolytic anemia can vary depending on the provider and the specific tests ordered. At DNA Labs India, our NGS genetic DNA test for G6PD deficiency hemolytic anemia costs INR 20,000.

Conclusion

G6PD deficiency hemolytic anemia can cause a range of symptoms and can be triggered by certain medications, infections, or foods. Diagnosis typically involves a blood test to measure G6PD activity, but genetic testing may be used in some cases. NGS genetic DNA testing is a powerful tool for identifying mutations in the G6PD gene that cause G6PD deficiency, and can provide more detailed information than traditional blood tests. If you are concerned about G6PD deficiency hemolytic anemia, talk to your healthcare provider about the best testing options for you.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for G6PD Gene Hemolytic anemia due to G6PD deficiency NGS Genetic DNA Test