Short Description

NGS genetic DNA test detecets for variant and mutation detection in FLRT1 gene for SPG68, FLRT1 related

PreTest Information

Clinical History of Patient who is going for FLRT1 Gene SPG68, FLRT1 related NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with FLRT1 Gene SPG68, FLRT1 related

Detail Description

Understanding the FLRT1 Gene and SPG68

FLRT1 gene, also known as Fibronectin Leucine-Rich Transmembrane protein 1, is responsible for encoding a protein that plays an essential role in the development of the nervous system. The FLRT1 gene is located on chromosome 3 and is involved in the formation of synapses, which are crucial for the transmission of signals between neurons.

SPG68, also known as Hereditary Spastic Paraplegia Type 68, is a rare genetic disorder that affects the nervous system. It is caused by mutations in the FLRT1 gene, which leads to the development of spasticity, muscle weakness, and difficulty walking.

Diagnosis of SPG68

SPG68 is diagnosed through genetic testing, which involves analyzing the FLRT1 gene for mutations. Next-generation sequencing (NGS) is a commonly used method for genetic testing, which can detect mutations in multiple genes simultaneously.

Symptoms of SPG68

The symptoms of SPG68 typically begin in early childhood and worsen over time. They include:

• Difficulty walking
• Stiffness and muscle weakness in the legs
• Unsteady gait
• Foot drop
• Urinary urgency and incontinence

Cost of FLRT1-related NGS Genetic DNA Test

The cost of FLRT1-related NGS Genetic DNA Test in India is approximately INR 20,000. However, the cost may vary depending on the laboratory and the type of test performed.

Conclusion

FLRT1 gene mutations can lead to SPG68, a rare genetic disorder that affects the nervous system. Genetic testing, such as NGS, can help diagnose SPG68 and other genetic disorders. If you or someone you know is experiencing symptoms of SPG68, consult a healthcare professional for proper diagnosis and treatment.

At DNA Labs India, we provide reliable and accurate genetic testing services for a wide range of genetic disorders, including SPG68. Our team of experts uses advanced technologies to analyze DNA samples and provide accurate results. Contact us today to learn more about our services.

Remember, early diagnosis and treatment can improve the quality of life for individuals with genetic disorders.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for FLRT1 Gene SPG68, FLRT1 related NGS Genetic DNA Test