Short Description

NGS genetic DNA test detecets for variant and mutation detection in FLCN gene for Birt-Hogg-Dube syndrome

PreTest Information

Clinical History of Patient who is going for FLCN Gene Birt-Hogg-Dube syndrome NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with FLCN Gene Birt-Hogg-Dube syndrome NGS Genetic DNA Test gene FLCN

Detail Description

FLCN Gene and Birt-Hogg-Dube Syndrome: Understanding Symptoms, Diagnosis, and NGS Genetic DNA Test Cost in India

Birt-Hogg-Dube Syndrome (BHDS) is a rare genetic disorder that can cause skin lesions, lung cysts, and kidney tumors. It is caused by mutations in the FLCN gene, which provides instructions for making a protein that helps regulate cell growth and division. BHDS is inherited in an autosomal dominant pattern, meaning that a person only needs to inherit one mutated copy of the FLCN gene to develop the condition.

While BHDS is a rare condition, it is important for individuals with a family history of the disorder or symptoms associated with it to seek medical evaluation. Early diagnosis and treatment can help prevent serious complications such as kidney cancer.

Symptoms of Birt-Hogg-Dube Syndrome

The symptoms of BHDS can vary widely between individuals, and some people may not experience any symptoms at all. Common symptoms of BHDS include:

• Multiple skin lesions, typically located on the face, neck, and upper body
• Lung cysts, which may cause shortness of breath and a persistent cough
• Kidney tumors, which may not cause any symptoms in the early stages

Diagnosing Birt-Hogg-Dube Syndrome

If you or a family member are experiencing symptoms of BHDS, your doctor may recommend genetic testing to confirm a diagnosis. This typically involves a blood test or a cheek swab to collect a sample of DNA for analysis. A genetic counselor can help you understand the results of the test and the implications for your health and the health of your family members.

In addition to genetic testing, your doctor may recommend imaging tests such as a CT scan or MRI to look for lung cysts or kidney tumors. If a tumor is found, a biopsy may be performed to determine if it is cancerous or benign.

NGS Genetic DNA Test Cost in India for Birt-Hogg-Dube Syndrome

Next-generation sequencing (NGS) is a powerful tool for genetic testing that can analyze multiple genes at once. The cost of NGS testing for BHDS in India can vary depending on the laboratory and the specific tests ordered, but generally ranges from INR 20,000 to INR 30,000.

It is important to choose a reputable laboratory for genetic testing to ensure accurate results and proper interpretation of the findings. DNA Labs India is a leading provider of genetic testing services in India, with a team of experienced genetic counselors and laboratory technicians who can guide you through the testing process and help you understand the results.

Conclusion

Birt-Hogg-Dube Syndrome is a rare genetic disorder that can cause skin lesions, lung cysts, and kidney tumors. If you or a family member are experiencing symptoms of BHDS, it is important to seek medical evaluation and consider genetic testing to confirm a diagnosis. DNA Labs India offers NGS genetic DNA testing for BHDS at a cost of INR 20,000 to INR 30,000, with a team of experts who can guide you through the testing process and help you understand the results.

Early diagnosis and treatment of BHDS can help prevent serious complications, so don't hesitate to seek medical attention if you have concerns about your health or the health of a loved one.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for FLCN Gene Birt-Hogg-Dube syndrome NGS Genetic DNA Test