Short Description

Synovial Sarcoma accounts for 5-10% of soft-tissue sarcomas. They harbor the t(X18)(p11.2q11.2), resulting in the fusion of the SYT gene at 18q11 with either the SSX1 or the SSX2 gene (or, rarely, SSX4), which is a primary cytogenetic anomaly in 90% of the cases. Detection of this translocation is highly specific for Synovial Sarcoma. Break-apart rearrangement assays by FISH have been found more suitable for detection of the t(X18) in Synovial sarcoma, given the presence of multiple partner loci.

PreTest Information

Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.

Detail Description

FISH - SYNOVIAL SARCOMA (SS18 / SYT ) 18q11.2 GENE REARRANGEMENT Test Cost INR:12000 Symptoms Diagnosis

DNA Labs India offers the FISH - Synovial Sarcoma (SS18 / SYT) 18q11.2 Gene Rearrangement Test for INR 12000. This test is used to diagnose synovial sarcoma, a rare type of cancer that affects the soft tissues of the body.

Symptoms of Synovial Sarcoma

Synovial sarcoma can occur anywhere in the body, but it most commonly affects the arms, legs, hands, and feet. The symptoms of synovial sarcoma can vary depending on the location of the tumor. Some common symptoms include:

• A lump or mass that is painless or tender to the touch
• Swelling or inflammation around the affected area
• Numbness or tingling in the affected area
• Difficulty moving the affected limb

Diagnosing Synovial Sarcoma

If you are experiencing any of the symptoms of synovial sarcoma, it is important to see a doctor right away. Your doctor will perform a physical examination and may order imaging tests such as an MRI or CT scan to look for any abnormalities in the affected area.

If a tumor is found, a biopsy will be performed to determine if it is cancerous. In some cases, a FISH - Synovial Sarcoma (SS18 / SYT) 18q11.2 Gene Rearrangement Test may be ordered to confirm the diagnosis.

The FISH - Synovial Sarcoma (SS18 / SYT) 18q11.2 Gene Rearrangement Test

The FISH - Synovial Sarcoma (SS18 / SYT) 18q11.2 Gene Rearrangement Test is a genetic test that looks for a specific genetic rearrangement that is found in synovial sarcoma. This test is performed on a tissue sample taken from the tumor.

The test works by using fluorescent probes to target specific genes on the chromosome. If the genes are rearranged in a way that is consistent with synovial sarcoma, the probes will light up under a microscope, indicating a positive result.

Cost and Availability

The FISH - Synovial Sarcoma (SS18 / SYT) 18q11.2 Gene Rearrangement Test is available at DNA Labs India for INR 12000. The test is performed on a tissue sample taken from the tumor, which can be obtained through a biopsy.

Conclusion

The FISH - Synovial Sarcoma (SS18 / SYT) 18q11.2 Gene Rearrangement Test is an important tool in the diagnosis of synovial sarcoma. If you are experiencing any symptoms of this rare type of cancer, it is important to see a doctor right away. With early detection and treatment, the prognosis for synovial sarcoma can be favorable.

For more information about the FISH - Synovial Sarcoma (SS18 / SYT) 18q11.2 Gene Rearrangement Test or to schedule an appointment, contact DNA Labs India today.

Synovial Sarcoma accounts for 5-10% of soft-tissue sarcomas. They harbor the t(X;18)(p11.2;q11.2), resulting in the fusion of the SYT gene at 18q11 with either the SSX1 or the SSX2 gene (or, rarely, SSX4), which is a primary cytogenetic anomaly in 90% of the cases. Detection of this translocation is highly specific for Synovial Sarcoma. Break-apart rearrangement assays by FISH have been found more suitable for detection of the t(X;18) in Synovial sarcoma, given the presence of multiple partner loci.