Short Description

FIP1L1-PDGFRA rearrangement is generally found in Chronic Eosinophilic Leukemia, but the presentation can be as AML, T-lymphoblastic lymphoma, or both simultaneously. Rearrangement is usually cryptic by routine cytogenetics.

PreTest Information

Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.

Detail Description

FISH - PDGFR ALPHA (4q12) GENE REARRANGEMENT Test: Symptoms, Diagnosis, and Cost

DNA Labs India is a leading diagnostic center providing a range of genetic tests, including the FISH - PDGFR ALPHA (4q12) GENE REARRANGEMENT Test. This test is used to detect rearrangements in the PDGFR alpha gene, which is associated with certain types of cancer.

Symptoms

The symptoms of cancer associated with PDGFR alpha gene rearrangements can vary depending on the specific type of cancer. However, some common symptoms include:

• Unexplained weight loss
• Fatigue
• Pain or discomfort
• Lumps or masses
• Changes in bowel or bladder habits
• Difficulty breathing
• Jaundice

If you are experiencing any of these symptoms, it is important to see a healthcare professional for an accurate diagnosis.

Diagnosis

The FISH - PDGFR ALPHA (4q12) GENE REARRANGEMENT Test is a genetic test that is used to detect rearrangements in the PDGFR alpha gene. This test can be performed on a variety of sample types, including blood, bone marrow, and tissue samples.

To perform the test, a small sample of the patient's DNA is extracted and analyzed using fluorescent in situ hybridization (FISH) technology. This technology allows for the visualization of specific genes and chromosomal regions, making it possible to detect rearrangements in the PDGFR alpha gene.

If the test results are positive for PDGFR alpha gene rearrangements, additional testing may be necessary to determine the specific type of cancer and the best course of treatment.

Cost

The cost of the FISH - PDGFR ALPHA (4q12) GENE REARRANGEMENT Test at DNA Labs India is INR 6000. This cost includes the analysis of the patient's DNA sample and the interpretation of the test results by a qualified healthcare professional.

While this test may not be covered by all insurance plans, it is important to discuss your options with your healthcare provider and insurance company to determine the most cost-effective approach to testing.

Conclusion

The FISH - PDGFR ALPHA (4q12) GENE REARRANGEMENT Test is an important diagnostic tool for detecting rearrangements in the PDGFR alpha gene, which is associated with certain types of cancer. If you are experiencing symptoms of cancer or have a family history of cancer, it is important to discuss the possibility of genetic testing with your healthcare provider. DNA Labs India offers affordable and accurate genetic testing services, including the FISH - PDGFR ALPHA (4q12) GENE REARRANGEMENT Test.

FIP1L1-PDGFRA rearrangement is generally found in Chronic Eosinophilic Leukemia, but the presentation can be as AML, T-lymphoblastic lymphoma, or both simultaneously. Rearrangement is usually cryptic by routine cytogenetics.